Articles | Volume 67, issue 1
https://doi.org/10.5194/aab-67-51-2024
https://doi.org/10.5194/aab-67-51-2024
Original study
 | 
07 Feb 2024
Original study |  | 07 Feb 2024

Polymorphisms of the BMPR1B, BMP15 and GDF9 fecundity genes in four Chinese sheep breeds

Jinxin Wang, Yufang Liu, Siwu Guo, Ran Di, Xiangyu Wang, Xiaoyun He, and Mingxing Chu

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Cited articles

Abdoli, R., Zamani, P., Deljou, A., and Rezvan, H.: Association of BMPR-1B and GDF9 genes polymorphisms and secondary protein structure changes with reproduction traits in Mehraban ewes, Gene, 524, 296–303, 2013. 
Abdoli, R., Zamani, P., Mirhoseini, S. Z., Ghavi, H. Z. N., and Nadri, S.: A review on prolificacy genes in sheep, Reprod. Domest. Anim., 51, 631–637, 2016. 
Abir, R. and Fisch, B.: A single nucleotide polymorphism in BMP15 is associated with high response to controlled ovarian hyperstimulation, Reprod. BioMed. Online, 23, 77–80, 2011. 
Bindon, B. M.: Biology of the Booroola Merino sheep, Aust. J. Biol. Sci., 37, 163–189, 1984. 
Bodensteiner, K. J., Clay, C. M., Moeller, C. L., and Sawyer, H. R.: Molecular cloning of the ovine growth/differentiation factor-9 gene and expression of growth/differentiation factor-9 in ovine and bovine ovaries, Biol. Reprod., 60, 381–386, 1999. 
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Short summary
Finding polymorphisms of genes can provide potential molecular genetic markers for sheep reproduction. This study investigated the polymorphisms of three major reproductive genes (BMPR1B, BMP15 and GDF9) in Chinese sheep and found that BMPR1B and GDF9 might be the major genes influencing the reproductive performance of Chinese sheep breeds. This result might contribute to improving the prolificacy traits of native Chinese sheep in the future.