Archives Animal Breeding
Archives Animal Breeding
AAB
Articles | Volume 67, issue 2
Articles | Volume 67, issue 2
https://doi.org/10.5194/aab-67-153-2024
© Author(s) 2024. This work is distributed under
the Creative Commons Attribution 4.0 License.
https://doi.org/10.5194/aab-67-153-2024
© Author(s) 2024. This work is distributed under
the Creative Commons Attribution 4.0 License.
Articles | Volume 67, issue 2
Original study
 | 
11 Apr 2024
Original study |  | 11 Apr 2024

Polymorphisms of the HRG, FETUB, and GUCY1A1 genes and their association with litter size in sheep

Zizhen Ren, Xiaoyun He, Xiangyu Wang, and Mingxing Chu

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Banerjee, P., Jana, S. K., Pasricha, P., Ghosh, S., Chakravarty, B., and Chaudhury, K.: Proinflammatory cytokines induced altered expression of cyclooxygenase-2 gene results in unreceptive endometrium in women with idiopathic recurrent spontaneous miscarriage, Fertil. Steril., 99, 179–187, https://doi.org/10.1016/j.fertnstert.2012.08.034, 2013. 
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Cao, X. L., Song, J. Y., and Sun, Z. G.: Quantitative label-free proteomic analysis of human follicle fluid to identify novel candidate protein biomarker for endometriosis-associated infertility, J. Proteomics, 266, 104680, https://doi.org/10.1016/j.jprot.2022.104680, 2022. 
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Short summary
The g.405442728A>G locus of HRG exhibited moderate polymorphism (0.25<PIC<0.5) in these breeds, indicating this locus has great selection potential. It is accurate to say HRG can be used as a molecular marker to increase litter size in Small-tailed Han sheep (STH). The g.405442728A>G locus of HRG and the g.421655951C>T locus of FETUB had a significant effect on litter size in STH (P<0.05). We can use HRG and FETUB as candidate genes for the selection of litter size in sheep breeding.
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