Articles | Volume 67, issue 2
Original study
11 Apr 2024
Original study |  | 11 Apr 2024

Polymorphisms of the HRG, FETUB, and GUCY1A1 genes and their association with litter size in sheep

Zizhen Ren, Xiaoyun He, Xiangyu Wang, and Mingxing Chu


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Short summary
The g.405442728A>G locus of HRG exhibited moderate polymorphism (0.25<PIC<0.5) in these breeds, indicating this locus has great selection potential. It is accurate to say HRG can be used as a molecular marker to increase litter size in Small-tailed Han sheep (STH). The g.405442728A>G locus of HRG and the g.421655951C>T locus of FETUB had a significant effect on litter size in STH (P<0.05). We can use HRG and FETUB as candidate genes for the selection of litter size in sheep breeding.