Articles | Volume 59, issue 2
https://doi.org/10.5194/aab-59-167-2016
https://doi.org/10.5194/aab-59-167-2016
Original study
 | 
15 Apr 2016
Original study |  | 15 Apr 2016

Effect of purmorphamine on the mRNA expression of Sonic Hedgehog signaling downstream molecules in ovine embryo

Parisa Nadri, Saeid Ansari-Mahyari, and Azadeh Zahmatkesh

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Cited articles

Camous, S., Kopecny, V., and Flechon, J. E.: Autoradiographic detection of the earliest stage of [3H]-uridine incorporation into the cow embryo, Biol. Cell., 58, 195–200, 1986.
Crozet, N., Huneau, D., Desmedt, V., Theron, M. C., Szollosi, D., Torres, S., and Sevellec, C.: In vitro fertilization with normal development in the sheep, Gamete. Res., 16, 159–170, 1987.
Driancourt, M. A. and Thuel, B.: Control of oocyte growth and maturation by follicular cells and molecules present in follicular fluid, Reprod. Nutr. Dev. rev., 38, 345–362, 1998.
Elia, D., Madhala, D., Ardon, E., Reshef, R., and Halevy, O.: Sonic hedgehog promotes proliferation and differentiation of adult muscle cells: involvement of MAPK/ERK and PI3K/Akt pathway, Biochim. Biophy. Acta., 1773, 1438–1446, 2007.
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In this research, the effect of purmorphamine on mRNA expression of the SHH signaling downstream molecules Ptch1, Gli1, Smo, Hdac1, Hdac2 and Hdac3 in ovine two-cell embryos was studied. Regarding the presence of SHH signaling molecules in two-cell embryos and their response to purmorphamine, it can be suggested that SHH signaling is probably active before embryonic genome activation in ovine embryos.