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Articles | Volume 59, issue 2
Articles | Volume 59, issue 2
https://doi.org/10.5194/aab-59-167-2016
© Author(s) 2016. This work is distributed under
the Creative Commons Attribution 3.0 License.
https://doi.org/10.5194/aab-59-167-2016
© Author(s) 2016. This work is distributed under
the Creative Commons Attribution 3.0 License.
Articles | Volume 59, issue 2
Original study
 | 
15 Apr 2016
Original study |  | 15 Apr 2016

Effect of purmorphamine on the mRNA expression of Sonic Hedgehog signaling downstream molecules in ovine embryo

Parisa Nadri, Saeid Ansari-Mahyari, and Azadeh Zahmatkesh

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Short summary
In this research, the effect of purmorphamine on mRNA expression of the SHH signaling downstream molecules Ptch1, Gli1, Smo, Hdac1, Hdac2 and Hdac3 in ovine two-cell embryos was studied. Regarding the presence of SHH signaling molecules in two-cell embryos and their response to purmorphamine, it can be suggested that SHH signaling is probably active before embryonic genome activation in ovine embryos.
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