Articles | Volume 66, issue 4
Original study
13 Oct 2023
Original study |  | 13 Oct 2023

CircGUCY2C regulates cofilin 1 by sponging miR-425-3p to promote the proliferation of porcine skeletal muscle satellite cells

Kunlong Qi, Yaqing Dou, Chenlei Li, Yingke Liu, Chenglei Song, Xinjian Li, Kejun Wang, Ruimin Qiao, Xiuling Li, Feng Yang, and Xuelei Han

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Cited articles

Ashwal-Fluss, R., Meyer, M., Pamudurti, N. R., Ivanov, A., Bartok, O., Hanan, M., Evantal, N., Memczak, S., Rajewsky, N., and Kadener, S.: CircRNA biogenesis competes with pre-mRNA splicing, Mol. Cell, 56, 55–66,, 2014. 
Bi, P. and Kuang, S.: Meat science and muscle biology symposium: stem cell niche and postnatal muscle growth, J. Anim. Sci., 90, 924–935,, 2012. 
Brocks, L., Klont, R. E., Buist, W., de Greef, K., Tieman, M., and Engel, B.: The effects of selection of pigs on growth rate vs leanness on histochemical characteristics of different muscles, J. Anim. Sci., 78, 1247–1254,, 2000. 
Capel, B., Swain, A., Nicolis, S., Hacker, A., Walter, M., Koopman, P., Goodfellow, P., and Lovell-Badge, R.: Circular transcripts of the testis-determining gene Sry in adult mouse testis, Cell, 73, 1019–1030,, 1993. 
Chan, B. K. C.: Data analysis using R programming, Adv. Exp. Med. Biol., 1082, 47–122,, 2018. 
Short summary
With the rapid development of sequencing technology, it has been found that circRNAs play an important role in skeletal muscle development. During the growth and development of livestock, the growth and development of muscle fibers are closely related to the number, proliferation, and differentiation capacity of skeletal muscle satellite cells, thereby affecting meat quality. Notably, more and more studies now suggest that changes in circRNA expression may be associated with meat quality.