Archives Animal Breeding
Archives Animal Breeding
AAB
Articles | Volume 65, issue 4
Articles | Volume 65, issue 4
https://doi.org/10.5194/aab-65-357-2022
© Author(s) 2022. This work is distributed under
the Creative Commons Attribution 4.0 License.
https://doi.org/10.5194/aab-65-357-2022
© Author(s) 2022. This work is distributed under
the Creative Commons Attribution 4.0 License.
Articles | Volume 65, issue 4
Original study
 | 
10 Oct 2022
Original study |  | 10 Oct 2022

Bta-miR-33a affects gene expression and lipid levels in Chinese Holstein mammary epithelial cells

Ping Jiang, Ambreen Iqbal, Zhiqian Cui, Haibin Yu, and Zhihui Zhao

Related authors

The effect of short/branched chain acyl-coenzyme A dehydrogenase gene on triglyceride synthesis of bovine mammary epithelial cells
Ping Jiang, Xibi Fang, Zhihui Zhao, Xianzhong Yu, Boxing Sun, Haibin Yu, and Runjun Yang
Arch. Anim. Breed., 61, 115–122, https://doi.org/10.5194/aab-61-115-2018,https://doi.org/10.5194/aab-61-115-2018, 2018
Short summary
PSAP gene variants and haplotypes reveal significant effects on carcass and meat quality traits in Chinese Simmental-cross cattle
Pengcheng Guo, Zhihui Zhao, Shouqing Yan, Junya Li, Hang Xiao, Dongxue Yang, Yaolu Zhao, Ping Jiang, and Runjun Yang
Arch. Anim. Breed., 59, 461–468, https://doi.org/10.5194/aab-59-461-2016,https://doi.org/10.5194/aab-59-461-2016, 2016
Short summary
AGPAT6 gene EX1_303T > C and EX12_299G > A mutations and associations with economic traits of Chinese Simmental-cross cattle
Xiaojuan Long, Xibi Fang, Ping Jiang, Hang Xiao, Haibin Yu, Mengjiao Zhou, Yunzhi Pan, Chunyan Lu, Zhihui Zhao, and Runjun Yang
Arch. Anim. Breed., 59, 301–307, https://doi.org/10.5194/aab-59-301-2016,https://doi.org/10.5194/aab-59-301-2016, 2016
Short summary

Related subject area

Subject: Product quality | Animal: Cattle
Stability of fatty acid composition of intramuscular fat from pasture- and grain-fed young bulls during the first 7 d postmortem
Alberto Horcada, Oliva Polvillo, Pedro González-Redondo, Adoración López, David Tejerina, and Susana García-Torres
Arch. Anim. Breed., 63, 45–52, https://doi.org/10.5194/aab-63-45-2020,https://doi.org/10.5194/aab-63-45-2020, 2020
Short summary
Cows fed hydroponic fodder and conventional diet: effects on milk quality
Alan Agius, Grazia Pastorelli, and Everaldo Attard
Arch. Anim. Breed., 62, 517–525, https://doi.org/10.5194/aab-62-517-2019,https://doi.org/10.5194/aab-62-517-2019, 2019
Short summary
Carcass characteristics and meat quality of Holstein-Friesian  ×  Hereford cattle of different sex categories and slaughter ages
Paulina Pogorzelska-Przybyłek, Zenon Nogalski, Monika Sobczuk-Szul, Cezary Purwin, and Dorota Kubiak
Arch. Anim. Breed., 61, 253–261, https://doi.org/10.5194/aab-61-253-2018,https://doi.org/10.5194/aab-61-253-2018, 2018
Short summary
Effect of breed and aging time on physicochemical and organoleptic quality of beef and its oxidative stability
Ewa Sosin-Bzducha and Michał Puchała
Arch. Anim. Breed., 60, 191–198, https://doi.org/10.5194/aab-60-191-2017,https://doi.org/10.5194/aab-60-191-2017, 2017
Cytological quality of milk of primiparous cows kept in cubicles bedded with separated manure
Stanisław Winnicki, Zbigniew Sobek, Ryszard Kujawiak, Jerzy Jugowar, Anna Nienartowicz-Zdrojewska, and Jolanta Różańska-Zawieja
Arch. Anim. Breed., 60, 19–26, https://doi.org/10.5194/aab-60-19-2017,https://doi.org/10.5194/aab-60-19-2017, 2017
Short summary

Cited articles

Ambros, V.: The functions of animal microRNAs, Nature, 431, 350–355, https://doi.org/10.1038/nature02871, 2004. 
Bartel, D. P.: MicroRNAs: Genomics, Biogenesis, Mechanism, and Function, Cell, 116, 281–297, https://doi.org/10.1016/S0092-8674(04)00045-5, 2004. 
Benatti, R. O., Melo, A. M., Borges, F. O., Ignacio-Souza, L. M., Simino, L. A. P., Milanski, M., Velloso, L. A., Torsoni, M. A., and Torsoni, A. S.: Maternal high-fat diet consumption modulates hepatic lipid metabolism and microRNA-122 (miR-122) and microRNA-370 (miR-370) expression in offspring, Br. J. Nutr., 111, 2112–2122, https://doi.org/10.1017/S0007114514000579, 2014. 
Bond, L. M., Miyazaki, M., O'Neill, L. M., Ding, F., and Ntambi, J. M.: Fatty Acid Desaturation and Elongation in Mammals, in: Biochemistry of Lipids, Lipoproteins and Membranes, 6th Edn., Elsevier, 185–208, https://doi.org/10.1016/B978-0-444-63438-2.00006-7, 2016. 
Dávalos, A., Goedeke, L., Smibert, P., Ramírez, C. M., Warrier, N. P., Andreo, U., Cirera-Salinas, D., Rayner, K., Suresh, U., Pastor-Pareja, J. C., Esplugues, E., Fisher, E. A., Penalva, L. O. F., Moore, K. J., Suárez, Y., Lai, E. C., and Fernández-Hernando, C.: miR-33a/b contribute to the regulation of fatty acid metabolism and insulin signaling, P. Natl. Acad. Sci. USA, 108, 9232–9237, https://doi.org/10.1073/pnas.1102281108, 2011. 
More articles (34)
Download
Short summary
We present a novel study of the effect of bta-miR-33a on lipid metabolism in bovine mammary epithelial cells (BMECs). The correlation between bta-miR-33a and target gene ELOVL6 is also verified by a luciferase reporter assay. We show that bta-miR-33a directly inhibits the expression of ELOVL6 in BMECs, altering the mRNA expression of relative genes. This suggest that bta-miR-33a regulates lipid metabolism by targeting ELOVL6, which might be a potential molecular marker of milk fat composition.
Read more