Articles | Volume 65, issue 4
https://doi.org/10.5194/aab-65-357-2022
https://doi.org/10.5194/aab-65-357-2022
Original study
 | 
10 Oct 2022
Original study |  | 10 Oct 2022

Bta-miR-33a affects gene expression and lipid levels in Chinese Holstein mammary epithelial cells

Ping Jiang, Ambreen Iqbal, Zhiqian Cui, Haibin Yu, and Zhihui Zhao

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Latest update: 15 Jul 2024
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Short summary
We present a novel study of the effect of bta-miR-33a on lipid metabolism in bovine mammary epithelial cells (BMECs). The correlation between bta-miR-33a and target gene ELOVL6 is also verified by a luciferase reporter assay. We show that bta-miR-33a directly inhibits the expression of ELOVL6 in BMECs, altering the mRNA expression of relative genes. This suggest that bta-miR-33a regulates lipid metabolism by targeting ELOVL6, which might be a potential molecular marker of milk fat composition.