Articles | Volume 68, issue 1
https://doi.org/10.5194/aab-68-135-2025
https://doi.org/10.5194/aab-68-135-2025
Original study
 | 
12 Feb 2025
Original study |  | 12 Feb 2025

Correlation and regression analysis of the KRT27 and ELOVL4 genes in cashmere fineness and other production performances in Liaoning cashmere goats

Hua Ma, Weihang Hong, Lingjun Nie, Shuaitong Li, Qingyu Yuan, Ran Duan, Qiying Zhan, Lingchao Kong, and Zeying Wang

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Cited articles

Agbaga, M. P., Mandal, M. N., and Anderson, R. E.: Retinal very long-chain PUFAs: new insights from studies on ELOVL4 protein, J. Lipid Res., 51, 1624–1642, https://doi.org/10.1194/jlr.R005025, 2010. 
Braun, M., Reinartz, S., Heppelmann, M., Rehage, J., Sürie, C., Distl, O., and Metzger, J.: Curly coat caused by a keratin 27 variant was transmitted from Fleckvieh into German Angus, Anim. Genet., 49, 349–350, https://doi.org/10.1111/age.12669, 2018. 
Cai, W., Xu, Y., Bai, Z., Lin, G., Wang, L., Dou, X., Han, D., Wang, Z., Wang, J., Zhang, X., Zhang, Y., Qin, Y., Gu, M., Sun, Y., Wu, Y., Chen, R., and Wang, Z.: Association analysis for SNPs of BAAT and COL1A1 genes with cashmere production performance and other production traits in Liaoning cashmere goats, Anim. Biotechnol., 34, 2324–2335, https://doi.org/10.1080/10495398.2022.2088550, 2023. 
Diao, X., Yao, L., Wang, X., Li, S., Qin, J., Yang, L., He, L., and Zhang, W.: Hair Follicle Development and Cashmere Traits in Albas Goat Kids, Animals, 13, 617, https://doi.org/10.3390/ani13040617, 2023. 
Hopiavuori, B. R., Anderson, R. E., and Agbaga, M. P.: ELOVL4: Very long-chain fatty acids serve an eclectic role in mammalian health and function, Prog. Retin. Eye Res., 69, 137–158, https://doi.org/10.1016/j.preteyeres.2018.10.004, 2019. 
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Short summary
This study investigated single-nucleotide polymorphism (SNP) in the keratin 27 (KRT27, 1919G/A) and elongation of very-long-chain fatty acids 4 (ELOVL4, 28666C/T) genes, which are associated with production traits in Liaoning cashmere goats. Multivariate analysis was also conducted. The GGCC genotype combination was associated with finer cashmere quality. The GGTT haplotype exhibited a multigenic effect. The TT genotype demonstrated pleiotropy.
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