Articles | Volume 64, issue 1
https://doi.org/10.5194/aab-64-35-2021
https://doi.org/10.5194/aab-64-35-2021
Original study
 | 
29 Jan 2021
Original study |  | 29 Jan 2021

Effects of polymorphism of the GPAM gene on milk quality traits and its relation to triglyceride metabolism in bovine mammary epithelial cells of dairy cattle

Haibin Yu, Yaolu Zhao, Ambreen Iqbal, Lixin Xia, Zitong Bai, Hao Sun, Xibi Fang, Runjun Yang, and Zhihui Zhao

Related authors

Bta-miR-33a affects gene expression and lipid levels in Chinese Holstein mammary epithelial cells
Ping Jiang, Ambreen Iqbal, Zhiqian Cui, Haibin Yu, and Zhihui Zhao
Arch. Anim. Breed., 65, 357–370, https://doi.org/10.5194/aab-65-357-2022,https://doi.org/10.5194/aab-65-357-2022, 2022
Short summary
The effect of acyl-CoA synthetase long-chain family member 5 on triglyceride synthesis in bovine preadipocytes
Xiang Yu, Xibi Fang, Hang Xiao, Zhihui Zhao, Steffen Maak, Mengyan Wang, and Runjun Yang
Arch. Anim. Breed., 62, 257–264, https://doi.org/10.5194/aab-62-257-2019,https://doi.org/10.5194/aab-62-257-2019, 2019
Short summary
Polymorphisms of the ASIP gene and the haplotype are associated with fat deposition traits and fatty acid composition in Chinese Simmental steers
Yinuo Liu, Xibi Fang, Zhihui Zhao, Junya Li, Elke Albrecht, Lisa Schering, Steffen Maak, and Runjun Yang
Arch. Anim. Breed., 62, 135–142, https://doi.org/10.5194/aab-62-135-2019,https://doi.org/10.5194/aab-62-135-2019, 2019
Short summary
The effect of short/branched chain acyl-coenzyme A dehydrogenase gene on triglyceride synthesis of bovine mammary epithelial cells
Ping Jiang, Xibi Fang, Zhihui Zhao, Xianzhong Yu, Boxing Sun, Haibin Yu, and Runjun Yang
Arch. Anim. Breed., 61, 115–122, https://doi.org/10.5194/aab-61-115-2018,https://doi.org/10.5194/aab-61-115-2018, 2018
Short summary
PSAP gene variants and haplotypes reveal significant effects on carcass and meat quality traits in Chinese Simmental-cross cattle
Pengcheng Guo, Zhihui Zhao, Shouqing Yan, Junya Li, Hang Xiao, Dongxue Yang, Yaolu Zhao, Ping Jiang, and Runjun Yang
Arch. Anim. Breed., 59, 461–468, https://doi.org/10.5194/aab-59-461-2016,https://doi.org/10.5194/aab-59-461-2016, 2016
Short summary

Related subject area

Subject: DNA markers and gene expressions | Animal: Cattle
Mitochondrial DNA diversity of D-loop region in three native Turkish cattle breeds
Eymen Demir, Nina Moravčíková, Bahar Argun Karsli, Radovan Kasarda, Ibrahim Aytekin, Umit Bilginer, and Taki Karsli
Arch. Anim. Breed., 66, 31–40, https://doi.org/10.5194/aab-66-31-2023,https://doi.org/10.5194/aab-66-31-2023, 2023
Short summary
Assessment of the association of the MOGAT1 and MOGAT3 gene with growth traits in different growth stages in Holstein calves
Gökhan Gökçe and Mervan Bayraktar
Arch. Anim. Breed., 65, 301–308, https://doi.org/10.5194/aab-65-301-2022,https://doi.org/10.5194/aab-65-301-2022, 2022
Short summary
Genetic polymorphism of Pit-1 and CSN3 genes in Holstein calves and its associations with calf birth weight
Ismail Fındık and Memis Özdemir
Arch. Anim. Breed., 65, 285–292, https://doi.org/10.5194/aab-65-285-2022,https://doi.org/10.5194/aab-65-285-2022, 2022
Short summary
The relationships between κ-casein (CSN3) gene polymorphism and some performance traits in Simmental cattle
Hamiye Ünal and Sinan Kopuzlu
Arch. Anim. Breed., 65, 129–134, https://doi.org/10.5194/aab-65-129-2022,https://doi.org/10.5194/aab-65-129-2022, 2022
Short summary
Allele-specific polymerase chain reaction for the discrimination of elite Korean cattle associated with high beef quality and quantity
Wonhee Lee, Insik Nam, Daehyun Kim, Kukdong Kim, and Yoonseok Lee
Arch. Anim. Breed., 65, 47–53, https://doi.org/10.5194/aab-65-47-2022,https://doi.org/10.5194/aab-65-47-2022, 2022
Short summary

Cited articles

Bell, R. M. and Coleman, R. A.: Enzymes of glycerolipid synthesis in eukaryotes, Annu. Rev. Biochem., 49, 459–487, https://doi.org/10.1146/annurev.bi.49.070180.002331, 1980. 
Beuzen, N. D., Stear, M. J., and Chang, K. C.: Molecular markers and their use in animal breeding, Vet. J., 160, 42–52, https://doi.org/10.1053/tvjl.2000.0468, 2000. 
Bionaz, M., Baumrucker, C. R., Shirk, E., Vanden Heuvel, J. P., Block, E., and Varga, G. A.: Characterization of Madin-Darby bovine kidney cell line for peroxisome proliferator-activated receptors: temporal response and sensitivity to fatty acids, J. Dairy Sci., 91, 2808–2813, https://doi.org/10.3168/jds.2007-0789, 2008. 
Coleman, R. A. and Haynes, E. B.: Selective changes in microsomal enzymes of triacylglycerol and phosphatidylcholine synthesis in fetal and postnatal rat liver. Induction of microsomal sn-glycerol 3-phosphate and dihydroxyacetonephosphate acyltransferase activities, J. Biol. Chem., 258, 450–456, 1983. 
Coleman, R. A., Reed, B. C., Mackall, J. C., Student, A. K., Lane, M. D., and Bell, R. M.: Selective changes in microsomal enzymes of triacylglycerol phosphatidylcholine, and phosphatidylethanolamine biosynthesis during differentiation of 3T3-L1 preadipocytes, J. Biol. Chem., 253, 7256–7261, 1978. 
Download
Short summary
In this study, we examine the correlation between the expression of GPAM and adipogenesis in bovine mammary epithelial cells (bMECs). Additionally, three novel polymorphisms are identified within the bovine key functional domain of GPAM. GPAM plays a pivotal role in the regulation of phospholipid levels and cellular triacylglycerol, and its mutations could serve as a competent molecular marker that could be utilized for marker-assisted selection.