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AAB | Articles | Volume 62, issue 1
Arch. Anim. Breed., 62, 59–68, 2019
https://doi.org/10.5194/aab-62-59-2019
© Author(s) 2019. This work is distributed under
the Creative Commons Attribution 4.0 License.
Arch. Anim. Breed., 62, 59–68, 2019
https://doi.org/10.5194/aab-62-59-2019
© Author(s) 2019. This work is distributed under
the Creative Commons Attribution 4.0 License.

Original study 20 Feb 2019

Original study | 20 Feb 2019

DNA methylation pattern of the goat PITX1 gene and its effects on milk performance

Haiyu Zhao et al.

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Cited articles

Carcangiu, V., Arfuso, F., Luridiana, S., Giannetto, C., Rizzo, M., Bini, P. P., and Piccione, G.: Relationship between different livestock managements and stress response in dairy ewes, Arch. Anim. Breed., 61, 37–41, https://doi.org/10.5194/aab-61-37-2018, 2018. 
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Chavatte-Palmer, P., Velazquez, M. A., Jammes, H., and Duranthon, V.: Review: Epigenetics, developmental programming and nutrition in herbivores, Animal, 24, 1–9, 2018. 
Cocolakis, E., Dai, M., Drevet, L., Ho, J., Haines, E., Ali, S., and Lebrun, J. J.: Smad signaling antagonizes STAT5-mediated gene transcription and mammary epithelial cell differentiation, J. Biol. Chem., 283, 1293–1307, 2008. 
Cui, Y., Yan, H., Wang, K., Xu, H., Zhang, X., Zhu, H., Liu, J., Qu, L., Lan, X., and Pan, C.: Insertion/Deletion within the KDM6A gene is significantly associated with litter size in goat, Frontiers in Genetics, 9, 91, https://doi.org/10.3389/fgene.2018.00091, 2018. 
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This study analyzed the DNA methylation profile of the PITX1 gene and its relevance to lactation performance in goats. The methylation rates of the overall CpG island and the 3rd and 12th CpG-dinucleotide loci in blood were significantly associated with average milk yield. The overall methylation rates of the CpG island in mammary gland tissue from dry and lactation periods showed a significant difference. These results could be used as potential epigenetic markers for lactation performance.
This study analyzed the DNA methylation profile of the PITX1 gene and its relevance to lactation...
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