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Archives Animal Breeding Archiv Tierzucht
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This study analyzed the DNA methylation profile of the PITX1 gene and its relevance to lactation performance in goats. The methylation rates of the overall CpG island and the 3rd and 12th CpG-dinucleotide loci in blood were significantly associated with average milk yield. The overall methylation rates of the CpG island in mammary gland tissue from dry and lactation periods showed a significant difference. These results could be used as potential epigenetic markers for lactation performance.
AAB | Articles | Volume 62, issue 1
Arch. Anim. Breed., 62, 59–68, 2019
https://doi.org/10.5194/aab-62-59-2019
Arch. Anim. Breed., 62, 59–68, 2019
https://doi.org/10.5194/aab-62-59-2019

Original study 20 Feb 2019

Original study | 20 Feb 2019

DNA methylation pattern of the goat PITX1 gene and its effects on milk performance

Haiyu Zhao et al.

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Short summary
This study analyzed the DNA methylation profile of the PITX1 gene and its relevance to lactation performance in goats. The methylation rates of the overall CpG island and the 3rd and 12th CpG-dinucleotide loci in blood were significantly associated with average milk yield. The overall methylation rates of the CpG island in mammary gland tissue from dry and lactation periods showed a significant difference. These results could be used as potential epigenetic markers for lactation performance.
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