Articles | Volume 61, issue 4
Arch. Anim. Breed., 61, 433–439, 2018
Arch. Anim. Breed., 61, 433–439, 2018

Original study 02 Nov 2018

Original study | 02 Nov 2018

Effects of polymorphisms in CAPN1 and CAST genes on meat tenderness of Chinese Simmental cattle

Xiaomei Sun et al.

Related authors

Characterization of different adipose depots in fattened buffalo: histological features and expression profiling of adipocyte markers
Jieping Huang, Xiaoyan Liu, Xue Feng, Mingming Zhang, Kaixing Qu, Jianyong Liu, Xuefeng Wei, Bizhi Huang, and Yun Ma
Arch. Anim. Breed., 63, 61–67,,, 2020
Short summary

Related subject area

Subject: DNA markers and gene expressions | Animal: Cattle
Determination of the association of GHR/AluI gene polymorphisms with milk yield traits in Holstein and Jersey cattle raised in Turkey
Ozden Cobanoglu, Ertugrul Kul, Eser K. Gurcan, Samet H. Abaci, and Soner Cankaya
Arch. Anim. Breed., 64, 417–424,,, 2021
Short summary
Regulating glycolysis and heat shock proteins in Gannan yaks (Bos grunniens) in response to hypoxia of the Qinghai–Tibet Plateau
Yuliang Wen, Jiqing Wang, Xiu Liu, Shaobin Li, Jiang Hu, and Yuzhu Luo
Arch. Anim. Breed., 64, 345–353,,, 2021
Short summary
Variation in bovine leptin gene affects milk fatty acid composition in New Zealand Holstein Friesian  ×  Jersey dairy cows
Ishaku Lemu Haruna, Huitong Zhou, and Jon G. H. Hickford
Arch. Anim. Breed., 64, 245–256,,, 2021
Short summary
Detection of genetic variation and activity analysis of the promoter region of the cattle tRNA-modified gene TRDMT1
Xiaohua Yi, Shuai He, Shuhui Wang, Haidong Zhao, Mingli Wu, Shirong Liu, and Xiuzhu Sun
Arch. Anim. Breed., 64, 147–155,,, 2021
Short summary
Regulation of microRNA-33, SREBP and ABCA1 genes in a mouse model of high cholesterol
Xianglun Zhang, Hongbo Zhao, Qingkai Sheng, Xiaomu Liu, Wei You, Haichao Lin, and Guifen Liu
Arch. Anim. Breed., 64, 103–108,,, 2021

Cited articles

Allais, S., Journaux, L., Levéziel, H., Payet-Duprat, N., Raynaud, P., Hocquette, J.-F., Lepetit, J., Rousset, S., Denoyelle, C., and Bernard-Capel, C.: Effects of polymorphisms in the calpastatin and µ-calpain genes on meat tenderness in 3 French beef breeds, J. Anim. Sci., 89, 1–11, 2011. 
Barendse, W., Harrison, B. E., Hawken, R. J., Ferguson, D. M., Thompson, J. M., Thomas, M. B., and Bunch, R. J.: Epistasis between calpain 1 and its inhibitor calpastatin within breeds of cattle, Genetics, 176, 2601–2610, 2007. 
Buzanskas, M. E., Ventura, R. V., Chud, T. C. S., Bernardes, P. A., de Abreu Santos, D. J., de Almeida Regitano, L. C., de Alencar, M. M., de Alvarenga Mudadu, M., Zanella, R., and da Silva, M. V. G. B.: Study on the introgression of beef breeds in Canchim cattle using single nucleotide polymorphism markers, PloS One, 12, e0171660,, 2017. 
Calvo, J., Iguácel, L., Kirinus, J., Serrano, M., Ripoll, G., Casasús, I., Joy, M., Pérez-Velasco, L., Sarto, P., and Albertí, P.: A new single nucleotide polymorphism in the calpastatin (CAST) gene associated with beef tenderness, Meat Sci., 96, 775–782, 2014. 
Casas, E., White, S., Wheeler, T., Shackelford, S., Koohmaraie, M., Riley, D., Chase, C., Johnson, D., and Smith, T.: Effects of and μ-markers in beef cattle on tenderness traits, J. Anim. Sci., 84, 520–525, 2006. 
Short summary
Genetic markers are important tools for beef cattle breeding. Our work suggests that CAPN1 genetic markers have a positive effect on meat tenderness and marbling traits, the most important meat quality traits for consumers. The associations between the genotyped SNPs in this research and meat quality traits are of potential interest to the beef industry and could lay an important foundation for the expanding panel of functional variation relevant to meat quality.