Articles | Volume 59, issue 1
Arch. Anim. Breed., 59, 91–95, 2016
https://doi.org/10.5194/aab-59-91-2016
Arch. Anim. Breed., 59, 91–95, 2016
https://doi.org/10.5194/aab-59-91-2016

Original study 17 Feb 2016

Original study | 17 Feb 2016

Indels within the bovine visfatin gene affect its mRNA expression in longissimus muscle and subcutaneous fat

H. Cai et al.

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Cited articles

Bailey, S. D., Loredo-Osti, J. C., Lepage, P., Faith, J., Fontaine, J., Desbiens, K. M., Hudson, T. J., Bouchard, C., Gaudet, D., Perusse, L., Vohl, M. C., and Engert, J. C.: Common polymorphisms in the promoter of the visfatin gene (PBEF1) influence plasma insulin levels in a French-Canadian population, Diabetes, 55, 2896–2902, 2006.
Blakemore, A. I., Meyre, D., Delplanque, J., Vatin, V., Lecoeur, C., Marre, M., Tichet, J., Balkau, B., Froguel, P., and Walley, A. J.: A rare variant in the visfatin gene (NAMPT/PBEF1) is associated with protection from obesity, Obesity, 17, 1549–1553, 2009.
Braun, T. and Gautel, M.: Transcriptional mechanisms regulating skeletal muscle differentiation, growth and homeostasis, Nat. Rev. Mol. Cell. Bio., 12, 349–361, 2011.
Chen, H., Xia, T., Zhou, L., Chen, X., Gan, L., Yao, W., Peng, Y., and Yang, Z.: Gene organization, alternate splicing and expression pattern of porcine visfatin gene, Domest. Anim. Endocrin., 32, 235–245, 2007.
Fulco, M., Cen, Y., Zhao, P., Hoffman, E. P., McBurney, M. W., Sauve, A. A., and Sartorelli, V.: Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt, Dev. Cell., 14, 661–673, 2008.
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Short summary
In this research, the effects of two indel loci of the visfatin gene on mRNA expression levels were studied. The results imply that the expression levels of bovine visfatin vary with age and its indels might be putative variants mediating the expression of the bovine visfatin gene. This study provides useful information for further functional studies of bovine visfatin.