Archives Animal Breeding
Archives Animal Breeding
AAB
Articles | Volume 67, issue 2
Articles | Volume 67, issue 2
https://doi.org/10.5194/aab-67-217-2024
© Author(s) 2024. This work is distributed under
the Creative Commons Attribution 4.0 License.
https://doi.org/10.5194/aab-67-217-2024
© Author(s) 2024. This work is distributed under
the Creative Commons Attribution 4.0 License.
Articles | Volume 67, issue 2
Original study
 | 
21 May 2024
Original study |  | 21 May 2024

Molecular characterization, function, tissue differential expression, and single-nucleotide polymorphism of buffalo TP53 gene

Lige Huang, Dan Sheng, Xinyang Fan, Ruixia Gao, and Yongwang Miao

Viewed

Total article views: 375 (including HTML, PDF, and XML)
HTML PDF XML Total Supplement BibTeX EndNote
286 70 19 375 34 10 12
  • HTML: 286
  • PDF: 70
  • XML: 19
  • Total: 375
  • Supplement: 34
  • BibTeX: 10
  • EndNote: 12
Views and downloads (calculated since 21 May 2024)
Cumulative views and downloads (calculated since 21 May 2024)

Viewed (geographical distribution)

Total article views: 381 (including HTML, PDF, and XML) Thereof 381 with geography defined and 0 with unknown origin.
Country # Views %
  • 1
1
 
 
 
 

Cited

Latest update: 20 Nov 2024
Download
Short summary
The aim of this study was to investigate the role of TP53 in buffalo lactation. The data showed that buffalo TP53 inhibited the expression of genes related to milk protein and milk fat in buffalo mammary epithelial cells by inhibiting the PI3K–AKT–mTOR pathway. These results suggest that TP53 negatively regulates the synthesis of milk protein and milk fat in buffalo through the PI3K–AKT–mTOR pathway. This study provides new insights into the functional role of TP53 in buffalo lactation.
Read more