Articles | Volume 67, issue 2
https://doi.org/10.5194/aab-67-185-2024
https://doi.org/10.5194/aab-67-185-2024
Original study
 | 
18 Apr 2024
Original study |  | 18 Apr 2024

Lysozyme as an alternative to antibiotics improves growth, antioxidants status, immunity, and intestinal bacteria in broiler chickens during the fattening period

Ibrahim T. El-Ratel, Mahmoud H. EL-Deep, Nada K. Alharbi, Worood A. A. Alyoubi, Khaled H. El-Kholy, Ahmed A. Badawy, Ahmed Ezzat Ahmed, Mohammed F. M. El Basuini, Mahmoud Alagawany, and Sara F. Fouda

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Cited articles

Abd El-Hack, M. E. and Alagawany, M.: Antibiotic Alternatives in Poultry and Fish Feed, Bentham Science Publishers, https://doi.org/10.2174/97898150490151220101, 2022. 
Abdel-Latif, M. A., El-Far, A. H., Elbestawy, A. R., Ghanem, R., Mousa, S. A., and Abd El-Hamid, H. S.: Exogenous dietary lysozyme improves the growth performance and gut microbiota in broiler chickens targeting the antioxidant and non-specific immunity mRNA expression, PLoS ONE, 12, e0185153, https://doi.org/10.1371/journal.pone.0185153, 2017. 
Abdel-Latif, M. A., El-Hamid, H. S. A., Emam, M., Noreldin, A. E., Helmy, Y. A., El-Far, A. H., and Elbestawy, A. R.: Dietary lysozyme and avilamycin modulate gut health, immunity, and growth rate in broilers, BMC Vet. Res., 20, 28, https://doi.org/10.1186/s12917-023-03871-2, 2024. 
Abu Hafsa, S. H., Mahmoud, A. E. M., Fayed, A. M. A., and Abdel-Azeem, A. S.: The effect of exogenous lysozyme supplementation on growth performance, caecal fermentation and microbiota, and blood constituents in growing rabbits, Animals, 31, 899, https://doi.org/10.3390/ani12070899, 2022. 
Alagawany, M., El-Hindawy, M. M., Mohamed, L. A., Bilal, R. M., and Soomro, J.: The use of cold pressed oils as eco-friendly alternatives for antibiotics in high and low-CP diets of laying Japanese quail, Anim. Biotechnol., 33, 816–823, https://doi.org/10.1080/10495398.2020.1837846, 2020. 
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Short summary
The present study aimed to evaluate the impact of dietary lysozyme levels on the growth performance, hematological and blood biochemical parameters, immunity, antioxidant capacity, and intestinal microbial count in broiler chickens. In conclusion, chicken egg lysozyme (50 mg kg−1), a promising alternative for antibiotics in broiler chickens' diet, can enhance growth performance, antioxidant status, immunity, and intestinal microbiota.