Articles | Volume 65, issue 4
https://doi.org/10.5194/aab-65-417-2022
https://doi.org/10.5194/aab-65-417-2022
Original study
 | 
17 Nov 2022
Original study |  | 17 Nov 2022

Screening of three-way crossbred combination and genetic effect analysis of the SNP in the CLPG gene in meat sheep

Jian Tao Wang, Guo Sen Wang, Yuan Fang Gong, Xian Qiao, Xiang Li, Gui Zhu Wang, Ying Zhen Zheng, Jian Guo Lv, Xiang Long Li, and Zheng Zhu Liu

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Cited articles

Bidwell, C. A., Waddell, J. N., Taxis, T. M., Yu, H., Tellam, R. L., Neary, M. K., and Cockett, N. E.: New insights into polar overdominance in callipyge sheep, Anim. Genet., 45, 51–61, https://doi.org/10.1111/age.12132, 2014. 
Chen, F. Y., Niu, H., Wang, J. Q., Lei, C. Z., Lan, X. Y., Zhang, C. L., Li, M. J., Hua, L. S., Wang, J., and Chen, H.: Polymorphism of DLK1 and CLPG gene and their association with phenotypic traits in Chinese cattle, Mol. Biol. Rep.,38, 243–248, https://doi.org/10.1007/s11033-010-0101-7, 2011. 
China Committee on Animal Genetic Resources: Animal Genetic Resources in China: Sheep and Goats, China Agriculture Press, Beijing, ISBN: 978-7-109-15881-8, 2011. 
Cockett, N. E., Smit, M. A., Bidwell, C. A., Segers, K., Hadfield, T. L., Snowder, G. D., Georges, M., and Charlier, C.: The callipyge mutation and other genes that affect muscle hypertrophy in sheep, Genet. Sel. Evol., 37, S65–81, https://doi.org/10.1186/1297-9686-37-S1-S65, 2005. 
Du, W. G., Li, X. C., Wu, X., and Liang, P.: Study on fattening performance of three-breed hybrid lamb between Dorper sheep and “Hantan hybrid progeny”, China Herbivore Science, 36, 67–68, 2016. 
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Short summary
Three-way crossbreeding was performed with Australian White, Dorper, and Charollais as terminal male parents and elite F1 hybrids of Australian × Han, Dorper × Han, and Charollais × Han as female parents. Based on the growth of three-way crossbred and Small-tailed Han lambs as well as the effects of CLPG, the offspring of male Australian White and female Charollais × Han showed apparent heterosis, and the individuals with the T allele had improved body weight and body size.