Articles | Volume 65, issue 3
https://doi.org/10.5194/aab-65-309-2022
https://doi.org/10.5194/aab-65-309-2022
Original study
 | 
12 Aug 2022
Original study |  | 12 Aug 2022

Meta-analysis of association between c.963A>G single-nucleotide polymorphism on BMP15 gene and litter size in goats

Emel Zergani, Amir Rashidi, Jalal Rostamzadeh, Mohammad Razmkabir, and Jens Tetens

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Cited articles

Ahlawata, S., Sharmaa, R., Royb, M., Mandakmalec, S., Prakashd, V., and Tantiaa, M. S.: Genotyping of Novel SNPs in BMPR1B, BMP15, and GDF9 Genes for Association with Prolificacy in Seven Indian Goat Breeds, Anim. Biotechnol., 27, 199–207, https://doi.org/10.1080/10495398.2016.1167706, 2016. 
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Short summary
Different studies have reported controversial results regarding the effects of c.963A>G polymorphism in the BMP15 gene on litter size in goats. We conducted a meta-analysis by using data of all published relevant studies to address this contradiction and found a significant association between c.963A>G polymorphism and litter size at birth under dominant and additive genetic models. The meta-analysis results revealed that the AA genotype could be positively connected with litter size in goats.