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Articles | Volume 64, issue 1
Articles | Volume 64, issue 1
https://doi.org/10.5194/aab-64-211-2021
© Author(s) 2021. This work is distributed under
the Creative Commons Attribution 4.0 License.
https://doi.org/10.5194/aab-64-211-2021
© Author(s) 2021. This work is distributed under
the Creative Commons Attribution 4.0 License.
Articles | Volume 64, issue 1
Original study
 | 
28 May 2021
Original study |  | 28 May 2021

The expression and mutation of BMPR1B and its association with litter size in small-tail Han sheep (Ovis aries)

Yu-Liang Wen, Xiao-Fei Guo, Lin Ma, Xiao-Sheng Zhang, Jin-Long Zhang, Sheng-Guo Zhao, and Ming-Xing Chu

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Short summary
The expression and polymorphism of the BMPR1B gene associated with litter size in small-tail Han (STH) sheep were determined. We found that BMPR1B was mainly expressed in reproduction-related tissues and was more highly expressed in the hypothalamus of polytocous than in monotocous ewes in the follicular and luteal phases. A new molecular marker was found and was negatively correlated with litter size in STH sheep. These results can provide a reference for selective sheep breeding.
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