Articles | Volume 63, issue 1
https://doi.org/10.5194/aab-63-155-2020
© Author(s) 2020. This work is distributed under
the Creative Commons Attribution 4.0 License.
the Creative Commons Attribution 4.0 License.
https://doi.org/10.5194/aab-63-155-2020
© Author(s) 2020. This work is distributed under
the Creative Commons Attribution 4.0 License.
the Creative Commons Attribution 4.0 License.
Screening the key genes of hair follicle growth cycle in Inner Mongolian Cashmere goat based on RNA sequencing
Rui Su
College of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia Autonomous Region, 010018, China
Key Laboratory of Animal Genetics, Breeding and Reproduction, Hohhot, Inner Mongolia Autonomous Region, 010018, China
Key Laboratory of Mutton Sheep Genetics and Breeding, Ministry of Agriculture and Rural Affairs, Hohhot, 010018, China
Engineering Research Center for Goat Genetics and Breeding, Hohhot, Inner Mongolia Autonomous Region, 010018, China
College of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia Autonomous Region, 010018, China
Lingtian Zhang
College of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia Autonomous Region, 010018, China
Xiaochun Yan
College of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia Autonomous Region, 010018, China
Fenghong Wang
College of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia Autonomous Region, 010018, China
Lei Zhang
College of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia Autonomous Region, 010018, China
Xian Qiao
College of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia Autonomous Region, 010018, China
Xiaokai Li
College of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia Autonomous Region, 010018, China
Jinquan Li
CORRESPONDING AUTHOR
College of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia Autonomous Region, 010018, China
Key Laboratory of Animal Genetics, Breeding and Reproduction, Hohhot, Inner Mongolia Autonomous Region, 010018, China
Key Laboratory of Mutton Sheep Genetics and Breeding, Ministry of Agriculture and Rural Affairs, Hohhot, 010018, China
Engineering Research Center for Goat Genetics and Breeding, Hohhot, Inner Mongolia Autonomous Region, 010018, China
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Cited
30 citations as recorded by crossref.
- Identification and Characterization of Circular RNAs (circRNAs) Using RNA-Seq in Two Breeds of Cashmere Goats L. Hu et al. https://doi.org/10.3390/genes14020331
- Comparative Skin Transcriptomics Reveals Key Regulators of Cashmere Fiber Production in Inner Mongolian Goats H. Riaz et al. https://doi.org/10.3390/ani16060927
- Screening of hair follicle telogen-associated circRNAs in sheep and construction of their ceRNA network H. Sun et al. https://doi.org/10.1016/j.ygeno.2024.110818
- Unlocking the genetic secrets of Dorper sheep: insights into wool shedding and hair follicle development X. Yuan et al. https://doi.org/10.3389/fvets.2024.1489379
- Genomic Inbreeding and Runs of Homozygosity Analysis of Cashmere Goat Q. Zhao et al. https://doi.org/10.3390/ani14081246
- Influence of mutations in the FGF-5 gene on wool performance in sheep (review) E. Klimanova et al. https://doi.org/10.31677/2072-6724-2023-68-3-225-235
- Integrated analysis of lncRNAs and mRNAs by RNA-Seq in secondary hair follicle development and cycling (anagen, catagen and telogen) of Jiangnan cashmere goat (Capra hircus) C. Wu et al. https://doi.org/10.1186/s12917-022-03253-0
- Integrated transcriptomic and proteomic analysis reveals molecular mechanisms of melatonin-regulated hair follicle growth in cashmere goats and comparative insights across goat breeds L. Xie et al. https://doi.org/10.1186/s12864-025-12263-9
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- The regulation mechanism of different hair types in inner Mongolia cashmere goat based on PI3K-AKT pathway and FGF21 G. Gong et al. https://doi.org/10.1093/jas/skac292
- Identification of the Key Genes Associated with Different Hair Types in the Inner Mongolia Cashmere Goat G. Gong et al. https://doi.org/10.3390/ani12111456
- Telomere-to-telomere genome assembly of a male goat reveals variants associated with cashmere traits H. Wu et al. https://doi.org/10.1038/s41467-024-54188-z
- Transcriptomic analysis of regulatory mechanisms in the telogen-anagen transition of ovine hair follicles N. Zhang et al. https://doi.org/10.1186/s12864-024-11059-7
- MicroRNA-mRNA Regulatory Networking Fine-Tunes Polyunsaturated Fatty Acid Synthesis and Metabolism in the Inner Mongolia Cashmere Goat Y. Xie et al. https://doi.org/10.3389/fgene.2021.649015
- MeRIP-seq data analysis and validation reveal the regulatory role of m6A modified circRNAs in the apoptosis of secondary hair follicle cells in Inner Mongolia cashmere goats R. Zhang et al. https://doi.org/10.1016/j.cbd.2025.101419
- Genetic diversity analysis of Inner Mongolia cashmere goats (Erlangshan subtype) based on whole genome re-sequencing R. Wang et al. https://doi.org/10.1186/s12864-024-10485-x
- Genetic diversity and population structure in five Inner Mongolia cashmere goat populations using whole-genome genotyping T. Zhang et al. https://doi.org/10.5713/ab.23.0424
- Genomic Selection for Early Growth Traits in Inner Mongolian Cashmere Goats Using ABLUP, GBLUP, and ssGBLUP Methods T. Zhang et al. https://doi.org/10.3390/ani15121733
- The Dynamic Change of Gene-Regulated Networks in Cashmere Goat Skin with Seasonal Variation S. Hu et al. https://doi.org/10.1007/s10528-021-10114-2
- Exploring the Cyclic Patterns of Secondary Hair Follicles in Cashmere Goats Based on Skin Transcriptome Data G. Gong et al. https://doi.org/10.3390/ani16142156
- The occupied proportion of hair follicle group in Inner Mongolia cashmere goat (Capra hircus) J. Zhang et al. https://doi.org/10.1016/j.smallrumres.2022.106667
- Deciphering the molecular drivers for cashmere/pashmina fiber production in goats: a comprehensive review M. Vasu et al. https://doi.org/10.1007/s00335-025-10109-z
- Proteomics Reveals the Role of PLIN2 in Regulating the Secondary Hair Follicle Cycle in Cashmere Goats C. Wu et al. https://doi.org/10.3390/ijms26062710
- Comparative analysis of skin transcriptome reveals differences of cashmere fineness in different body parts of Inner Mongolia cashmere goats B. Zhou et al. https://doi.org/10.5713/ab.25.0119
- Identification of Genes Related to Hair Follicle Cycle Development in Inner Mongolia Cashmere Goat by WGCNA G. Gong et al. https://doi.org/10.3389/fvets.2022.894380
- Five SNPs Within the FGF5 Gene Significantly Affect Both Wool Traits and Growth Performance in Fine-Wool Sheep (Ovis aries) H. Zhao et al. https://doi.org/10.3389/fgene.2021.732097
- Combining multiomics to analyze the molecular mechanism of hair follicle cycle change in cashmere goats from Inner Mongolia C. Zhang et al. https://doi.org/10.3389/fvets.2024.1405355
- Investigating RNA-Seq-based differential gene expression during hair follicle development in Angora goat skin S. Selçuk et al. https://doi.org/10.5187/jast.2024.e104
- Cashmere cyclic growth affected by different photoperiods alters DNA methylation patterns R. Zhao et al. https://doi.org/10.1080/26895293.2024.2393847
- Identification and Molecular Analysis of m6A-circRNAs from Cashmere Goat Reveal Their Integrated Regulatory Network and Putative Functions in Secondary Hair Follicle during Anagen Stage T. Hui et al. https://doi.org/10.3390/ani12060694
Latest update: 24 Aug 2026
Short summary
We tried to find important influencing factors of SHF growth cycle in skin tissue from Inner Mongolian Cashmere goats by RNA sequencing (RNA-Seq). Based on the results of comprehensive analysis of differentially expressed genes, GO enrichment and KEGG enrichment, we found that FGF5, FGFR1 and RRAS had an effect on the hair follicle growth cycle. The results of this study may provide a theoretical basis for further research on the growth and development of SHF in Inner Mongolian Cashmere goats.
We tried to find important influencing factors of SHF growth cycle in skin tissue from Inner...