Novel alternative splicing variants of <i>ACOX1</i> and their differential expression patterns in goats

Wu, Xian-Feng; Liu, Yuan; Gao, Cheng-Fang; Chen, Xin-Zhu; Zhang, Xiao-Pei; Li, Wen-Yang

doi:https://doi.org/10.5194/aab-61-59-2018

Articles | Volume 61, issue 1

https://doi.org/10.5194/aab-61-59-2018

© Author(s) 2018. This work is distributed under
the Creative Commons Attribution 4.0 License.

https://doi.org/10.5194/aab-61-59-2018

© Author(s) 2018. This work is distributed under
the Creative Commons Attribution 4.0 License.

Articles | Volume 61, issue 1

Original study

|

24 Jan 2018

Original study |

| 24 Jan 2018

Novel alternative splicing variants of ACOX1 and their differential expression patterns in goats

Xian-Feng Wu, Yuan Liu, Cheng-Fang Gao, Xin-Zhu Chen, Xiao-Pei Zhang, and Wen-Yang Li

Supplement

https://doi.org/10.5194/aab-61-59-2018-supplement

Data sets

Capra hircus breed Fuqing ACOX1 splice variant 1 (ACOX1) mRNA, complete cds, alternatively spliced X. Wu https://www.ncbi.nlm.nih.gov/nuccore/KX828848

Short summary

ACOX1 is vital for fatty acid oxidation and deposition. The alternative splicing events of ACOX1 have not been reported in goats. Here, we found a novel splice variant (ACOX1-SV1) and a complete isoform (ACOX1). ACOX1 and ACOX1-SV1 were expressed at high levels in the liver, spleen, brain and fat in kid and adult goats. In both groups, the mRNA level of ACOX1 was high in fat and that of ACOX1-SV1 was high in liver. These findings should provide new insights on the function of ACOX1.