Articles | Volume 61, issue 4
Arch. Anim. Breed., 61, 505–516, 2018
Arch. Anim. Breed., 61, 505–516, 2018

Original study 20 Dec 2018

Original study | 20 Dec 2018

Genetic polymorphism in melatonin receptor 1A and arylalkylamine N-acetyltransferase and its impact on seasonal reproduction in Egyptian sheep breeds

Hager A. Fathy et al.

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Cited articles

Aboul-Ela, M. B. and Chemineau, P.: Seasonality of reproductive activity in native sheep and goat breeds and their crosses with introduced breeds, in: Proceedings of Small ruminants research and development in the Near East, edited by: Aboul-Naga, A. M., IDRC (International Development Research Centre), Cairo, Egypt, 2–4 November 1988, 74–87, 1990. 
Ağaoğlu, Ö. K., Saatci, M., Akyüz, B., Elmaz, Ö., Çolak, M., Balkan, B. M., and Zeytünlü, E.: Melatonin receptor 1A gene RsaI and inhibin alpha subunit gene HaeII polymorphisms in Honamli and Hair goat breeds reared in Western Mediterranean region of Turkey, Turk, J. Vet. Anim. Sci., 39, 23–28,, 2015. 
Ahmad, T., Ganai, T. A. S., Magotra, A., Sharma, R. K., and Aarif, O.: Genetic polymorphism of melatonin receptor 1A (MTNR1A) gene in Corriedale sheep of Kashmir, India, Indian J. Anim. Res., 49, 448–450,, 2015. 
Ahmed, A. M.: Biological evaluation of Barki sheep under two different breeding seasons, Egyptian Journal of Animal Production, 45, 15–24, 2008. 
Avanus, K. and Altinel, A.: Identification of Genetic Variation of Melatonin Receptor 1A (MTNR1A) Gene in Kıvırcık Breed Ewes by MnlI and RsaI Restriction Enzymes, Kafkas Üniversitesi, Veteriner, Fakültesi, Dergisi., 22, 571–576,, 2016. 
Short summary
This study was carried out to detect polymorphisms in the melatonin receptor 1A and arylalkylamine N-acetyltransferase genes and their association with reproductive traits. Blood samples of 126 animals from three Egyptian sheep breeds were collected. DNA was extracted and subjected to PCR-restriction fragment length polymorphism analysis using the RsaI and SmaI enzymes. Two alleles (C and T) and three genotypes (CC, CT and TT) for MTNR1A and for AA-NAT (A and G; GG, GA and AA) were detected.