The microRNA gene bta-mir-2313 in cattle: an atlas of regulatory elements and an association analysis with growth and carcass traits in the Slovenian Simental cattle breed
Špela Malovrh,Tanja Kunej,Milena Kovač,and Peter Dovč
Špela Malovrh
Department of Animal Science, Biotechnical Faculty, University of
Ljubljana, Groblje 3, 1230 Domzale, Slovenia
Effects of miRNA polymorphisms on phenotypic traits have been studied in several species but much less in cattle. We tested the association between polymorphisms of bta-miR-2313 and growth and carcass traits in the Slovenian Simmental cattle breed and developed an atlas of miRNA regulatory elements. Bta-miR-2313 warrants further functional analysis since it overlaps with several QTL, has over 3100 predicted targets, and is located within GRAMD1B, associated with production traits in cattle.
Effects of miRNA polymorphisms on phenotypic traits have been studied in several species but...