Articles | Volume 60, issue 3
Arch. Anim. Breed., 60, 199–204, 2017
Arch. Anim. Breed., 60, 199–204, 2017

Original study 19 Jul 2017

Original study | 19 Jul 2017

Identification and expression analysis of miR-144-5p and miR-130b-5p in dairy cattle

Zhixiong Li et al.

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Cited articles

Baggiolini, M. and Loetscher, P.: Chemokines in inflammation and immunity, Immunol. Today, 21, 418–420, 2000.
Balkwill, F.: The significance of cancer cell expression of the chemokine receptor CXCR4, Semin. Cancer Biol., 14, 171–179, 2004.
Bannerman, D. D.: Pathogen-dependent induction of cytokines and other soluble inflammatory mediators during intramammary infection of dairy cows, J. Anim. Sci., 87, 10–25, 2005.
Bartel, D. P.: MicroRNAs, genomics, biogenesis, mechanism, and function, Cell, 116, 281–297, 2004.
Short summary
Bovine mastitis, a prevalent and complex infectious disease, can result in significant dairy cattle losses. MicroRNAs (miRNAs) play important roles in regulating innate and adaptive immune responses. The results in this paper show that the expression of miR-144-5p and miR-130b-5p in mastitis-infected mammary tissue was significantly downregulated and upregulated, respectively, compared to healthy tissue. Our findings may provide a method for the treatment of mastitis.