Articles | Volume 69, issue 2
https://doi.org/10.5194/aab-69-347-2026
https://doi.org/10.5194/aab-69-347-2026
Original study
 | 
25 Jun 2026
Original study |  | 25 Jun 2026

The role of ESR1 in regulating lactation traits in buffalo mammary epithelial cells

Zhixiang Wang, Xiaoyun Chen, Chaobin Qin, Jiaqi Jiang, Ling Li, Qingyou Liu, Cuijin Teng, Jinping Xiong, Leyi Wang, Ahmed Amin, and Zhipeng Li

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Short summary
Buffalo milk is valued for its rich flavor and high nutrition. However, the lag in genetic research has limited the utilization of buffalo lactation traits. This study found that ESR1 (estrogen receptor alpha) supports cell growth and health, enhances milk fat and protein production, and reduces cell damage. This work offers new insights for breeding and management to improve milk yield and quality, supporting more sustainable dairy production for farmers and consumers globally.
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