Articles | Volume 66, issue 4
https://doi.org/10.5194/aab-66-357-2023
https://doi.org/10.5194/aab-66-357-2023
Original study
 | 
23 Nov 2023
Original study |  | 23 Nov 2023

Genome-wide single nucleotide polymorphism (SNP) data reveal potential candidate genes for litter traits in a Yorkshire pig population

Yu Zhang, Jinhua Lai, Xiaoyi Wang, Mingli Li, Yanlin Zhang, Chunlv Ji, Qiang Chen, and Shaoxiong Lu

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Cited articles

Almuriekhi, M., Shintani, T., Fahiminiya, S., Fujikawa, A., Kuboyama, K., Takeuchi, Y., Nawaz, Z., Nadaf, J., Kamel, H., Kitam, A. K., Samiha, Z., Mahmoud, L., Ben-Omran, T., Majewski, J., and Noda, M.: Loss-of-function mutation in APC2 causes sotos syndrome features, Cell Rep., 10, 1585–1598, https://doi.org/10.1016/j.celrep.2015.02.011, 2015. 
Averaimo, S., Milton, R. H., Duchen, M. R., and Mazzanti, M.: Chloride intracellular channel 1 (CLIC1): Sensor and effector during oxidative stress, FEBS Lett., 584, 2076–2084, https://doi.org/10.1016/j.febslet.2010.02.073, 2010. 
Basini, G., Grasselli, F., Bussolati, S., Ciccimarra, R., Maranesi, M., Bufalari, A., Parillo, F., and Zerani, M.: Presence and function of kisspeptin/KISS1R system in swine ovarian follicles, Theriogenology, 115, 1–8, https://doi.org/10.1016/j.theriogenology.2018.04.006, 2018. 
Beharier, O., Kajiwara, K., and Sadovsky, Y.: Ferroptosis, trophoblast lipotoxic damage, and adverse pregnancy outcome, Placenta, 108, 32–38, https://doi.org/10.1016/j.placenta.2021.03.007, 2021. 
Bilokapic, S., Suskiewicz, M. J., Ahel, I., and Halic, M.: Bridging of DNA breaks activates PARP2-HPF1 to modify chromatin, Nature, 585, 609–613, https://doi.org/10.1038/s41586-020-2725-7, 2020. 
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Short summary
Litter traits are key indicators of the reproductive productivity of sows. In the present study, four litter traits (total number born, number born alive, piglets born dead, and litter weight born alive) were explored. Several candidate genes were identified by a genome-wide association study and selective sweep analysis. These findings provide novel insights into the genetic basis of pig litter traits and will be helpful for improving molecular breeding in pigs.