Articles | Volume 65, issue 3
Original study
04 Aug 2022
Original study |  | 04 Aug 2022

Genetic polymorphism of Pit-1 and CSN3 genes in Holstein calves and its associations with calf birth weight

Ismail Fındık and Memis Özdemir

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Cited articles

Akyüz, B. and Çınar, M. U.: Analysis of prolactin and kappa-casein genes polymorphism in four cattle breeds in Turkey, Ann. Anim. Sci., 14, 799–806,, 2014. 
Akyüz, B., Arslan K., Bayram, D., and İşcan, K. M.: Allelic frequency of kappa-casein, growth hormone and prolactin gene in Holstein, Brown Swiss and Simmental cattle breeds in Turkey, Kafkas Univ. Vet. Fak., 19, 439–444,, 2013. 
Aytekin, I. and Boztepe, S.: Associations of Pit-1 gene polymorphism with milk yield and composition traits in brown swiss cattle, J. Anim. Plant Sci., 23, 1281–1289, 2013. 
Bayram, D., Arslan, K., Akyuz, B., and Iscan, K. M.: Identification of pituitary-specific transcription factor-1 (PIT-1) and leptin gene (LEP) polymorphism of Holstein cattle reared in Turkey, Ankara Üniv. Vet. Fak., 64, 337–343,, 2017. 
Caroli, A. M., Chessa, S., and Erhardt, G. J.: Milk protein polymorphisms in cattle: effect on animal breeding and human nutrition, J. Dairy Sci., 92, 5335–5352,, 2009. 
Short summary
HinfI polymorphisms of Pit-1 and CSN3 genes were identified in DNA isolated from blood samples of 100 Holstein calves used in the study, using the PCR-RFLP method. According to the Hardy–Weinberg genetic equilibrium test, it was observed that the distribution of genotype frequencies of HinfI polymorphisms of Pit-1 genes in the studied population was in equilibrium, but not in equilibrium in terms of CSN3 gene location.