Articles | Volume 65, issue 2
Original study
21 Apr 2022
Original study |  | 21 Apr 2022

Association analysis of single-nucleotide polymorphism in prolactin and its receptor with productive and body conformation traits in Liaoning cashmere goats

Yanzhi Wu, Yu Zhang, Yuting Qin, Weidong Cai, Xinjiang Zhang, Yanan Xu, Xingtang Dou, Zhanhong Wang, Di Han, Jiaming Wang, Guangyu Lin, Lingling Wang, Jianjun Hao, Shuqing Fu, Rui Chen, Yinggang Sun, Zhixian Bai, Ming Gu, and Zeying Wang

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Cited articles

Bolefeysot, C., Goffin, V., Edery, M., Binart, N., and Kelly, P. A.: Prolactin (PRL) and Its Receptor: Actions, Signal Transduction Pathways and Phenotypes Observed in PRL Receptor Knockout Mice, Endocr. Rev., 19, 225–68,, 1998. 
Capparelli, R., Parlato, M., Amoroso, M. G., Roperto, S., Marabelli, R., Roperto, F., and Iannelli, D.: Mannose-binding lectin haplotypes influence Brucella abortus infection in the water buffalo (Bubalus bubalis), Immunogenetics, 60, 157–165,, 2008. 
Chang, Y., Bai, W. L., Zheng, Y. Y., Hui, T. Y., Sun, J. M., Guo, D., Guo, S. L., and Wang, Z. Y.: Correlation analysis of candidate gene SNP for high-yield in Liaoning cashmere goats with litter size and cashmere performance, Anim. Biotechnol., 32, 43–50,, 2019. 
Craven, A. J., Ormandy, C. J., Robertson, F. G., Wilkins, R. J., Kelly, P. A., Nixon, A. J., and Pearson, A. J.: Prolactin signaling influences the timing mechanism of the hair follicle: analysis of hair growth cycles in prolactin receptor knockout mice, Endocrinology, 142, 2533–2539,, 2001. 
Dahl, G. E.: Effects of short day photoperiod on prolactin signaling in dry cows: a common mechanism among tissues and environments?, J. Anim Sci., 86, 10–14,, 2008. 
Short summary
Our research tried new ideas and measured the milk production performance of cashmere goats and found that the nutritional indicators of milk of Liaoning cashmere goats were excellent, laying a theoretical foundation for the future development of breeding to cashmere goats. At the same time, it also provides theoretical support for producers and can screen individual genotypes based on the experimental results during seed selection, thereby improving production performance to a certain extent.