Articles | Volume 65, issue 1
https://doi.org/10.5194/aab-65-105-2022
https://doi.org/10.5194/aab-65-105-2022
Original study
 | 
10 Mar 2022
Original study |  | 10 Mar 2022

TIMP1 may affect goat prolificacy by regulating biological function of granulosa cells

Lei Hong, Xiang Chen, Min Zhu, Zheng Ao, Wen Tang, and Zhinan Zhou

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Latest update: 26 Dec 2024
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Short summary
Tissue inhibitor of metalloproteinase 1 (TIMP1) plays a crucial role in follicle growth and embryonic development. Ovarian granulosa cells also play an essential role in these processes. However, the effect of TIMP1 on the biological function of goat ovarian granulosa cells remains unknown. The objective of this study was to explore the impact of TIMP1 on granulosa cell proliferation and reproductive characteristics in goats.