Articles | Volume 64, issue 2
https://doi.org/10.5194/aab-64-335-2021
https://doi.org/10.5194/aab-64-335-2021
Original study
 | 
18 Aug 2021
Original study |  | 18 Aug 2021

Trehalose can effectively protect sheep epididymis epithelial cells from oxidative stress

Zhaojin Luan, Xiaomei Fan, Yongchao Zhao, Huizi Song, Wei Du, Jiaoxia Xu, Zhaochen Wang, Wenguang Zhang, and Jiaxin Zhang

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Latest update: 20 Nov 2024
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Short summary
In this work, we analyzed the effects of trehalose on sheep EEC proliferation and possible mechanisms affecting its role. Our study suggested that exogenous trehalose exhibits antioxidant activity through increasing the activities of CAT, GSH-Px, and the expression level of GPX5. The cell line cultured provides a strong resource for elucidating the transcriptional networks that coordinate functions of sheep epididymis epithelium and have greatly enhanced our understanding of epididymis biology.