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Articles | Volume 63, issue 2
Articles | Volume 63, issue 2
https://doi.org/10.5194/aab-63-461-2020
© Author(s) 2020. This work is distributed under
the Creative Commons Attribution 4.0 License.
https://doi.org/10.5194/aab-63-461-2020
© Author(s) 2020. This work is distributed under
the Creative Commons Attribution 4.0 License.
Articles | Volume 63, issue 2
Original study
 | 
10 Dec 2020
Original study |  | 10 Dec 2020

EDA and EDAR expression at different stages of hair follicle development in cashmere goats and effects on expression of related genes

Zhihong Wu, Yu Wang, Wenjing Han, Kun Yang, Erhan Hai, Rong Ma, Zhengyang Di, Fangzheng Shang, Rui Su, Ruijun Wang, Zhiying Wang, Yanjun Zhang, and Jinquan Li

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Short summary
This study provided a theoretical and experimental basis for further studying the molecular regulation mechanism of hair follicle development. EDA and EDAR were both expressed in the skin tissue in the seven cashmere goat embryo stages. Moreover, EDA and EDAR play an important role in the formation of embryonic placode (Pc). After interfering with EDA and EDAR, the expression of BMP2, BMP4, noggin, β-catenin, TGF-β2, Wnt-10b, and NOTCH1 in fibroblasts and epithelial cells changed significantly.
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