Articles | Volume 63, issue 2
Arch. Anim. Breed., 63, 461–470, 2020
https://doi.org/10.5194/aab-63-461-2020
Arch. Anim. Breed., 63, 461–470, 2020
https://doi.org/10.5194/aab-63-461-2020

Original study 10 Dec 2020

Original study | 10 Dec 2020

EDA and EDAR expression at different stages of hair follicle development in cashmere goats and effects on expression of related genes

Zhihong Wu et al.

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Latest update: 22 Jan 2022
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Short summary
This study provided a theoretical and experimental basis for further studying the molecular regulation mechanism of hair follicle development. EDA and EDAR were both expressed in the skin tissue in the seven cashmere goat embryo stages. Moreover, EDA and EDAR play an important role in the formation of embryonic placode (Pc). After interfering with EDA and EDAR, the expression of BMP2, BMP4, noggin, β-catenin, TGF-β2, Wnt-10b, and NOTCH1 in fibroblasts and epithelial cells changed significantly.