Articles | Volume 63, issue 2
Arch. Anim. Breed., 63, 249–259, 2020
https://doi.org/10.5194/aab-63-249-2020
Arch. Anim. Breed., 63, 249–259, 2020
https://doi.org/10.5194/aab-63-249-2020

Original study 22 Jul 2020

Original study | 22 Jul 2020

Molecular characterization, tissue expression and polymorphisms of buffalo PPARGC1A gene

Lihua Qiu et al.

Related authors

Polymorphism and molecular characteristics of the CSN1S2 gene in river and swamp buffalo
Xinyang Fan, Shanshan Gao, Lin Fu, Lihua Qiu, and Yongwang Miao
Arch. Anim. Breed., 63, 345–354, https://doi.org/10.5194/aab-63-345-2020,https://doi.org/10.5194/aab-63-345-2020, 2020
Short summary
Polymorphisms of the kappa casein (CSN3) gene and inference of its variants in water buffalo (Bubalus bubalis)
Xinyang Fan, Zifang Zhang, Lihua Qiu, Yongyun Zhang, and Yongwang Miao
Arch. Anim. Breed., 62, 585–596, https://doi.org/10.5194/aab-62-585-2019,https://doi.org/10.5194/aab-62-585-2019, 2019
Short summary

Related subject area

Subject: DNA markers and gene expressions | Animal: Ruminants
Polymorphism detection of DGAT1 and Lep genes in Anatolian water buffalo (Bubalus bubalis) populations in Turkey
Raziye Işık, Emel Özkan Ünal, and M. İhsan Soysal
Arch. Anim. Breed., 65, 1–9, https://doi.org/10.5194/aab-65-1-2022,https://doi.org/10.5194/aab-65-1-2022, 2022
Short summary
Comparative analysis of differentially expressed miRNAs related to uterine involution in the ovine ovary and uterus
Heng Yang, Lin Fu, Qifeng Luo, Licai Li, Fangling Zheng, Jiayu Wen, Xingxiu Luo, Chenjing Li, Zongsheng Zhao, Huihao Xu, and Gaofu Wang
Arch. Anim. Breed., 64, 167–175, https://doi.org/10.5194/aab-64-167-2021,https://doi.org/10.5194/aab-64-167-2021, 2021
Short summary
Identification and validation of key miRNAs and miRNA–mRNA regulatory network associated with uterine involution in postpartum Kazakh sheep
Heng Yang, Lin Fu, Qifeng Luo, Licai Li, Fangling Zheng, Jiayu Wen, Chenjing Li, Xingxiu Luo, Zongsheng Zhao, and Huihao Xu
Arch. Anim. Breed., 64, 119–129, https://doi.org/10.5194/aab-64-119-2021,https://doi.org/10.5194/aab-64-119-2021, 2021
Short summary
Association of β-casein gene polymorphism with milk composition traits of Egyptian Maghrebi camels (Camelus dromedarius)
Amira M. Nowier and Sherif I. Ramadan
Arch. Anim. Breed., 63, 493–500, https://doi.org/10.5194/aab-63-493-2020,https://doi.org/10.5194/aab-63-493-2020, 2020
Short summary
Polymorphism and molecular characteristics of the CSN1S2 gene in river and swamp buffalo
Xinyang Fan, Shanshan Gao, Lin Fu, Lihua Qiu, and Yongwang Miao
Arch. Anim. Breed., 63, 345–354, https://doi.org/10.5194/aab-63-345-2020,https://doi.org/10.5194/aab-63-345-2020, 2020
Short summary

Cited articles

Almagro-Armenteros, J. J., Tsirigos, K. D., Sønderby, C. K., Petersen, T. N., Winther, O., Brunak, S., von Heijne, G., and Nielsen, H.: SignalP 5.0 improves signal peptide predictions using deep neural networks, Nat. Biotechnol., 37, 420–423, https://doi.org/10.1038/s41587-019-0036-z, 2019. 
Bionaz, M. and Loor, J. J.: Gene networks driving bovine milk fat synthesis during the lactation cycle, BMC Genomics, 9, 366, https://doi.org/10.1186/1471-2164-9-366, 2008. 
Chen, Z., Luo, J., Sun, S., Cao, D., Shi, H., and Loor, J. J.: miR-148a and miR-17-5p synergistically regulate milk TAG synthesis via PPARGC1A and PPARA in goat mammary epithelial cells, RNA Biol., 14, 326–338, https://doi.org/10.1080/15476286.2016.1276149, 2017. 
D'Ambrosio, C., Arena, S., Salzano, A. M., Renzone, G., Ledda, L., and Scaloni, A.: A proteomic characterization of water buffalo milk fractions describing PTM of major species and the identification of minor components involved in nutrient delivery and defense against pathogens, Proteomics, 8, 3657–3666, https://doi.org/10.1002/pmic.200701148, 2008. 
Dominy, J. E., Lee, Y., Gerhart-Hines, Z., and Puigserver, P.: Nutrient-dependent regulation of PGC-1α's acetylation state and metabolic function through the enzymatic activities of Sirt1/GCN5, Biochim. Biophys. Acta, 1804, 1676–1683, https://doi.org/10.1016/j.bbapap.2009.11.023, 2010. 
Download
Short summary
In order to reveal whether peroxisome proliferator-activated receptor γ coactivator-1 α (PPARGC1A) gene is involved in the process of milk fat synthesis in buffalo, we analyzed the function and expression of this gene here. The results showed that buffalo PPARGC1A played a key role in the lipid synthesis of mammary gland. Eight SNPs were found in its coding region, of which three were non-synonymous. This study revealed that the PPARGC1A is closely related to buffalo milk fat synthesis.