Articles | Volume 62, issue 2
Arch. Anim. Breed., 62, 477–490, 2019
Arch. Anim. Breed., 62, 477–490, 2019

Original study 26 Jul 2019

Original study | 26 Jul 2019

Potential of TLR-gene diversity in Czech indigenous cattle for resistance breeding as revealed by hybrid sequencing

Karel Novák et al.

Related subject area

Subject: DNA markers and gene expressions | Animal: Cattle
Determination of the association of GHR/AluI gene polymorphisms with milk yield traits in Holstein and Jersey cattle raised in Turkey
Ozden Cobanoglu, Ertugrul Kul, Eser K. Gurcan, Samet H. Abaci, and Soner Cankaya
Arch. Anim. Breed., 64, 417–424,,, 2021
Short summary
Regulating glycolysis and heat shock proteins in Gannan yaks (Bos grunniens) in response to hypoxia of the Qinghai–Tibet Plateau
Yuliang Wen, Jiqing Wang, Xiu Liu, Shaobin Li, Jiang Hu, and Yuzhu Luo
Arch. Anim. Breed., 64, 345–353,,, 2021
Short summary
Variation in bovine leptin gene affects milk fatty acid composition in New Zealand Holstein Friesian  ×  Jersey dairy cows
Ishaku Lemu Haruna, Huitong Zhou, and Jon G. H. Hickford
Arch. Anim. Breed., 64, 245–256,,, 2021
Short summary
Detection of genetic variation and activity analysis of the promoter region of the cattle tRNA-modified gene TRDMT1
Xiaohua Yi, Shuai He, Shuhui Wang, Haidong Zhao, Mingli Wu, Shirong Liu, and Xiuzhu Sun
Arch. Anim. Breed., 64, 147–155,,, 2021
Short summary
Regulation of microRNA-33, SREBP and ABCA1 genes in a mouse model of high cholesterol
Xianglun Zhang, Hongbo Zhao, Qingkai Sheng, Xiaomu Liu, Wei You, Haichao Lin, and Guifen Liu
Arch. Anim. Breed., 64, 103–108,,, 2021

Cited articles

Abdel-Shafy, H., Bortfeldt, R. H., Tetens, J., and Brockmann, G. A.: Single nucleotide polymorphism and haplotype effects associated with somatic cell score in German Holstein cattle, Genet. Sel. Evol., 46, 35,, 2014. 
Anthoney, N., Foldi, I., and Hidalgo, A.: Toll and Toll-like receptor signalling in development, Development, 145, UNSP dev156018,, 2018. 
Beecher, C., Daly, M., Childs, S., Berry, D. P., Magee, D. A., McCarthy, T. V., and Giblin, L.: Polymorphisms in bovine immune genes and their associations with somatic cell count and milk production in dairy cattle, BMC Genet., 11, 99,, 2010. 
Bhaladhare, A., Sharma, D., Kumar, A., Sonwane, A., Chauhan, A., Singh, R., Kumar, P., Yadav, R., Baqir, M., Bhushan, B., and Prakash, O.: Single nucleotide polymorphisms in toll-like receptor genes and case-control association studies with bovine tuberculosis, Vet. World, 9, 458–464, 2016. 
Bilgen, N., Kul, B. C., Offord, V., Werling, D., and Ertugrul, O.: Determination of genetic variations of Toll-like receptor (TLR) 2, 4, and 6 with next-generation sequencing in native cattle breeds of Anatolia and Holstein Friesian, Diversity, 8, 23,, 2016. 
Short summary
Resequencing of diversity hidden in the innate-immunity genes of the TLR series in Czech Simmental, its conserved subpopulation, and the ancestral Czech Red cattle showed sufficient potential for infection resistance breeding regardless of the prevailing breeding for production traits on the one hand and a limited potential of diversity preserved in the historical populations on the other. The importance of the characterization of genetic resources to counteract changing infections is implied.