Articles | Volume 61, issue 1
Arch. Anim. Breed., 61, 71–78, 2018
https://doi.org/10.5194/aab-61-71-2018
Arch. Anim. Breed., 61, 71–78, 2018
https://doi.org/10.5194/aab-61-71-2018

Original study 02 Feb 2018

Original study | 02 Feb 2018

Identification of a novel 24 bp insertion–deletion (indel) of the androgen receptor gene and its association with growth traits in four indigenous cattle breeds

Haidong Zhao et al.

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Cited articles

Ahmad, H. I., Liu, G., Jiang, X., Liu, C., Xu, F. Z., Chong, Y., Ijaz, N., and Huang, H. R.: Adaptive selection at agouti gene inferred breed specific selection signature within the indigenous goat populations, Asian-Australas. J. Anim. Sci., https://doi.org/10.5713/ajas.16.0994, 2017. 
Chen, R., Yu, S., Ren, F., Lv, X. Y., and Pan, C. Y.: Detection of one large insertion/deletion (indel) and two novel SNPs within the SPEF2 gene and their associations with male piglet reproduction traits, Arch. Anim. Breed., 59, 275–283, https://doi.org/10.5194/aab-59-275-2016, 2016. 
Choi, J. W., Choi, B. H., Lee, S. H., Lee, S. S., Kim, H. C., Yu, D., Chung, W. H., Lee, K. T., Chai, H. H., Cho, Y. M., and Lim, D.: Whole-Genome resequencing analysis of hanwoo and yanbian cattle to identify genome-wide SNPs and signatures of selection, Mol Cells, 38, 466–473, 2015. 
Chorev, M. and Carmel, L.: Computational identification of functional introns: high positional conservation of introns that harbor RNA genes, Nucleic Acids Res., 41, 5604–5613, 2013. 
Cameron, J. L., Jain, R., Rais, M., White, A. E., Beer, T. M., Kievit, P., Winters-Stone, K., Messaoudi, I., and Varlamov, O.: Perpetuating effects of androgen deficiency on insulin resistance, Int. J. Obes. (Lond)., 40, 1856–1863, 2016. 
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Short summary
The androgen receptor (AR) plays the vital role of a bridge on the function of the androgen and has sexual size dimorphism. For this reason, the objective of this study was to explore the novel indel variants within the cattle AR gene and to detect a novel 24 bp indel within the AR gene. It significantly affected growth traits, suggesting that this indel may be a useful DNA marker for the elimination or selection of excellent individuals for cattle breeding.