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Short summary
ACADSB is a member of the acyl-CoA dehydrogenase family, which can catalyze the dehydrogenation of acyl-CoA derivatives in lipometabolism. Our previous transcriptome analysis results identified it as a differentially expressed gene in mammary tissue between low and high milk fat cattle. Current results showed that ACADSB expression level was positively correlated with cellular triglycerides content, and it was actively involved in fatty acid metabolism pathway in BME cell of dairy cattle.
AAB | Articles | Volume 61, issue 1
Arch. Anim. Breed., 61, 115–122, 2018
https://doi.org/10.5194/aab-61-115-2018
Arch. Anim. Breed., 61, 115–122, 2018
https://doi.org/10.5194/aab-61-115-2018

Original study 02 Mar 2018

Original study | 02 Mar 2018

The effect of short/branched chain acyl-coenzyme A dehydrogenase gene on triglyceride synthesis of bovine mammary epithelial cells

Ping Jiang et al.

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Cited articles

Alfardan, J., Mohsen, A. W., Copeland, S., Ellison, J., Keppen-Davis, L., Rohrbach, M., Powell, B. R., Gillis, J., Matern, D., Kant, J., and Vockley, J.: Characterization of new ACADSB gene sequence mutations and clinical implications in patients with 2-methylbutyrylglycinuria identified by newborn screening, Mol. Genet. Metab., 100, 333–338, https://doi.org/10.1016/j.ymgme.2010.04.014, 2010. 
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Arden, K. C., Viars, C. S., Fu, K., and Rozen, R.: Localization of short/branched chain acyl-CoA dehydrogenase (ACADSB) to human chromosome 10, Genomics, 25, 743–745, 1995. 
Ca, C., Cl, C., Leuzzi, V., Artiola, C., Santagata, S., De Luca, T., Vestri, L., and Antonozzi, I.: A new case of short/branched-chain acyl-CoA dehydrogenase deficiency caused by two novel mutations, J. Inherit. Metab. Dis., 30, 43–43, 2007. 
Chaudhari, A., Pathakota, G. B., and Annam, P. K.: Design and construction of shrimp antiviral DNA vaccines expressing long and short hairpins for protection by RNA interference, Methods in molecular biology, 1404, 225–240, https://doi.org/10.1007/978-1-4939-3389-1_16, 2016. 
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Short summary
ACADSB is a member of the acyl-CoA dehydrogenase family, which can catalyze the dehydrogenation of acyl-CoA derivatives in lipometabolism. Our previous transcriptome analysis results identified it as a differentially expressed gene in mammary tissue between low and high milk fat cattle. Current results showed that ACADSB expression level was positively correlated with cellular triglycerides content, and it was actively involved in fatty acid metabolism pathway in BME cell of dairy cattle.
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