Articles | Volume 60, issue 2
https://doi.org/10.5194/aab-60-61-2017
© Author(s) 2017. This work is distributed under
the Creative Commons Attribution 3.0 License.
the Creative Commons Attribution 3.0 License.
https://doi.org/10.5194/aab-60-61-2017
© Author(s) 2017. This work is distributed under
the Creative Commons Attribution 3.0 License.
the Creative Commons Attribution 3.0 License.
Effects of polymorphisms at LEP, CAST, CAPN1, GHR, FABP4 and DGAT1 genes on fattening performance and carcass traits in Simmental bulls
Sena Ardicli
Uludag University, Faculty of Veterinary Medicine, Department of
Genetics, Nilufer/BURSA, 16059, Turkey
Deniz Dincel
Uludag University, Faculty of Veterinary Medicine, Department of
Genetics, Nilufer/BURSA, 16059, Turkey
Hale Samli
Uludag University, Faculty of Veterinary Medicine, Department of
Genetics, Nilufer/BURSA, 16059, Turkey
Uludag University, Faculty of Veterinary Medicine, Department of
Genetics, Nilufer/BURSA, 16059, Turkey
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The LEP gene has been extensively studied in cattle, but research on goats is limited, often overlooking vital parameters like reproduction and growth. We investigate the relationship between LEP gene polymorphisms and growth or reproductive traits in Saanen goats. Notably, the LEP-Sau3AI SNP exhibited associations with birth weight and average daily weight gain. This pioneering study is the first to explore these traits alongside selected LEP variants in Saanen goats.
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Genetic selection based on bovine casein variants, especially for A2 milk, is a scorching topic in animal breeding and genetics. Our study assessed the genotypic/allelic frequencies, population genetics, diversity parameters, and relationship between genotypes and breeding values with respect to two casein genes, CSN2 and CSN3 in Holstein Friesian cows. The present results are critical for evaluating the genetic merit of cows in commercial dairy cattle breeding.
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We measured physical meat quality of a slow-growing broiler as an alternative to fast-growing broiler, and we used slatted floor housing and free-range production as alternatives to conventional deep litter. Taking into account genotype × housing system interactions for meat pH and shear force traits, a fast-growing broiler may be more appropriate for fully slated housing and a slow-growing broiler may be more suitable for a free-range housing system.
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An extensive genetic evaluation of cattle fattening performance was performed in this study. Fifteen SNPs in the LEP, FABP4, DGAT1, TG, IGF1, IGF1R, MYF5, LGB, CAPN1, CAST, GHR, and OLR1 genes were evaluated in 296 purebred Holstein–Friesian bulls using PCR-RFLP. This study clearly demonstrated that individual or combined effects of the genotypes at the selected genes may be effective on performance traits at different periods of animal growth and fattening.
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The impact of polymorphisms of the calpain 1 (CAPN1), calpastatin (CAST), leptin (LEP) and growth hormone receptor (GHR) on carcass characteristics and meat quality traits in 400 purebred Holstein bulls was examined using polymerase chain reaction and restriction fragment length polymorphism method. In the current study, the CAPN1, CAST and GHR genotypes confirmed significant associations with important traits in adequate numbers of animals.
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The LEP gene has been extensively studied in cattle, but research on goats is limited, often overlooking vital parameters like reproduction and growth. We investigate the relationship between LEP gene polymorphisms and growth or reproductive traits in Saanen goats. Notably, the LEP-Sau3AI SNP exhibited associations with birth weight and average daily weight gain. This pioneering study is the first to explore these traits alongside selected LEP variants in Saanen goats.
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DGAT1 influences milk yield and quality. Prior studies had limitations: small sample sizes, no environmental effects, and poor lactation records. Our study of 1104 Holstein Friesian and Jersey cows used polymerase chain reaction–restriction fragment length polymorphism (PCR-RFLP) and Sanger sequencing for genotyping. We evaluate genotypic and allelic frequencies, population genetics, and phenotypic effects. Our findings offer more reliable interpretations at both phenotypic and genotypic levels.
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Genetic selection based on bovine casein variants, especially for A2 milk, is a scorching topic in animal breeding and genetics. Our study assessed the genotypic/allelic frequencies, population genetics, diversity parameters, and relationship between genotypes and breeding values with respect to two casein genes, CSN2 and CSN3 in Holstein Friesian cows. The present results are critical for evaluating the genetic merit of cows in commercial dairy cattle breeding.
Melahat Özbek, Metin Petek, and Sena Ardıçlı
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We measured physical meat quality of a slow-growing broiler as an alternative to fast-growing broiler, and we used slatted floor housing and free-range production as alternatives to conventional deep litter. Taking into account genotype × housing system interactions for meat pH and shear force traits, a fast-growing broiler may be more appropriate for fully slated housing and a slow-growing broiler may be more suitable for a free-range housing system.
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An extensive genetic evaluation of cattle fattening performance was performed in this study. Fifteen SNPs in the LEP, FABP4, DGAT1, TG, IGF1, IGF1R, MYF5, LGB, CAPN1, CAST, GHR, and OLR1 genes were evaluated in 296 purebred Holstein–Friesian bulls using PCR-RFLP. This study clearly demonstrated that individual or combined effects of the genotypes at the selected genes may be effective on performance traits at different periods of animal growth and fattening.
Sena Ardicli, Hale Samli, Deniz Dincel, Bahadir Soyudal, and Faruk Balci
Arch. Anim. Breed., 60, 303–313, https://doi.org/10.5194/aab-60-303-2017, https://doi.org/10.5194/aab-60-303-2017, 2017
Short summary
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The impact of polymorphisms of the calpain 1 (CAPN1), calpastatin (CAST), leptin (LEP) and growth hormone receptor (GHR) on carcass characteristics and meat quality traits in 400 purebred Holstein bulls was examined using polymerase chain reaction and restriction fragment length polymorphism method. In the current study, the CAPN1, CAST and GHR genotypes confirmed significant associations with important traits in adequate numbers of animals.
Related subject area
Subject: Quantitative genetics and estimation of breeding value | Animal: Cattle
Expression pattern of ZNF33B in bovine ovaries and the effect of its polymorphism on superovulation traits
The effect of single-nucleotide polymorphisms within heat shock protein beta 1 on beef quantity in Korean native steers
Determination of genetic variation within the DYRK2 gene and its associations with milk traits in cattle
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Analysis of lactating cows on commercial Austrian dairy farms: the influence of genotype and body weight on efficiency parameters
Linking first lactation survival to milk yield and components and lactation persistency in Tunisian Holstein cows
Determination of a possible relationship between a single nucleotide polymorphism (SNP) in the promoter region of the SIRT1 gene and production and reproduction traits in the Agerolese cattle breed
(Co)variance components and genetics parameter estimation for linear traits in Holstein cattle in Indonesia: traits related to foot/leg and udder
Body weight prediction using body size measurements in Fleckvieh, Holstein, and Brown Swiss dairy cows in lactation and dry periods
Genetic parameters for longitudinal behavior and health indicator traits generated in automatic milking systems
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Genetic analysis of productive life length in Holstein dairy cows using Weibull proportional risk model
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Changhong Li, Peijun Xia, Yijuan Ma, Xinyue Zhang, and Yijia Liu
Arch. Anim. Breed., 65, 69–77, https://doi.org/10.5194/aab-65-69-2022, https://doi.org/10.5194/aab-65-69-2022, 2022
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In this study, we first studied the expression of ZNF33B in bovine ovaries and early embryos, and we determined the expression position and quantity of ZNF33B in ovaries and the temporal and spatial specificity of ZNF33B expression in early embryos. Secondly, the G-61G>T mutation of 5' UTR in ZNF33B gene was studied. The frequency of the G genotype was 0.3489 and that of the T genotype was 0.6511. This mutation was significantly correlated with the superovulation traits in cattle.
Jung-Keun Suh, Jae-Sung Lee, Hongsik Kong, Yoonseok Lee, and Hong-Gu Lee
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The relationship between HSPB1 expression and muscle growth in beef cattle has previously been reported, but there have been no reports of DNA markers related to meat quantity in Korean native steers. Therefore, the aim of this study was to evaluate the relationship of SNPs within HSPB1 in terms of the carcass traits related to muscle growth in Korean native steers.
Cui Mao, Xing Ju, Haijian Cheng, Xixia Huang, Fugui Jiang, Yuni Yao, Xianyong Lan, and Enliang Song
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Ishaku L. Haruna, Sibusiso A. Hadebe, Oyekunle J. Oladosu, Ghassan Mahmoud, Huitong Zhou, and Jon G. H. Hickford
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The aim of this study was to evaluate the influence of body weight on the efficiency of dairy cows. Data were derived from 161 commercial Austrian dairy farms. An optimum body weight range for efficiency does exist as the relationship of milk yield and body weight is nonlinear. Specialized dairy breeds seem to respond more intensively to body weight range than dual-purpose breeds. Cows with medium weights are the most efficient. A further increase in dairy cows’ body weights should be avoided.
Marwa Grayaa, Sylvie Vanderick, Boulbaba Rekik, Abderrahman Ben Gara, Christian Hanzen, Siwar Grayaa, Rodrigo Reis Mota, Hedi Hammami, and Nicolas Gengler
Arch. Anim. Breed., 62, 153–160, https://doi.org/10.5194/aab-62-153-2019, https://doi.org/10.5194/aab-62-153-2019, 2019
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The lactation curve and lactation survival are important in dairy cattle breeding. Their simultaneous improvement results in economic benefits. The genetic relationship between the lactation survival and the lactation curve shape traits of milk yield and fat and protein percentages using information from of 25 981 primiparous Tunisian Holsteins was investigated. Cows that had higher persistencies for fat and protein percentages were more likely not to survive.
Maria Selvaggi, Claudia Carbonara, Francesca Ciotola, Sara Albarella, Giulio Aiudi, Vincenzo Tufarelli, and Cataldo Dario
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The aims of the study were to estimate allele and genotype frequencies at g.-274C > G locus in the promoter region of the SIRT1 gene and to investigate, for the first time, the relationship among different genotypes and milk and reproduction traits in the Agerolese cattle breed. The investigated population was found to be polymorphic at the investigated locus. Concerning milk production performance, significant differences between genotypes were found.
Agus Susanto, Suyadi, Veronica Margareta Ani Nurgiartiningsih, and Luqman Hakim
Arch. Anim. Breed., 61, 491–496, https://doi.org/10.5194/aab-61-491-2018, https://doi.org/10.5194/aab-61-491-2018, 2018
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Improved milk yield in dairy cows results in worsening health and reproduction. Some linear traits are genetically associated with health and reproduction and can be used to assist selection programs. The National Breeding Centre for Dairy and Forage of Indonesia has not included linear traits in the breeding program. This study estimates genetic parameters of linear traits. The traits under study were found to be heritable and can be included in the breeding program along with milk yield.
Leonhard Gruber, Maria Ledinek, Franz Steininger, Birgit Fuerst-Waltl, Karl Zottl, Martin Royer, Kurt Krimberger, Martin Mayerhofer, and Christa Egger-Danner
Arch. Anim. Breed., 61, 413–424, https://doi.org/10.5194/aab-61-413-2018, https://doi.org/10.5194/aab-61-413-2018, 2018
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The objective of this study was to predict dairy cows' body weight from body size measurements. Body weight is an important trait for both management and breeding. Data were derived from 167 commercial Austrian dairy farms. To ensure high prediction accuracy, the use of a combination of both heart girth and belly girth is recommended if the use of scales is impossible. The large and heterogeneous data set supported a valid prediction.
Laura Viviana Santos, Kerstin Brügemann, Asja Ebinghaus, and Sven König
Arch. Anim. Breed., 61, 161–171, https://doi.org/10.5194/aab-61-161-2018, https://doi.org/10.5194/aab-61-161-2018, 2018
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The impact of the milking technique on the individual animal and the reaction of the animal on the technique were investigated. With the use of objectively recorded data from automatic milking systems (AMSs), auxiliary traits that reflect animal behavior in the milking system were defined, free from subjective impressions of classifiers. There is an apparent possibility to breed cows for AMS systems based on AMS data, though it is imperative to have further validation based on larger datasets.
Seyni Siddo, Nassim Moula, Issa Hamadou, Moumouni Issa, Salissou Issa, Marichatou Hamani, Pascal Leroy, and Nicolas Antoine-Moussiaux
Arch. Anim. Breed., 61, 143–151, https://doi.org/10.5194/aab-61-143-2018, https://doi.org/10.5194/aab-61-143-2018, 2018
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The complex balance between innovation and conservation regarding animal genetic resources makes it difficult to find mutually accepted improvement pathways between breeders, government agencies, and research and education institutions. This study maps stakeholder viewpoints on cattle genetic improvement in Niger using the Q method, which appears effective in identifying the concerns of stakeholders on complex agricultural innovation topics.
Danny Arends, Deike Hesse, and Gudrun A. Brockmann
Arch. Anim. Breed., 61, 87–98, https://doi.org/10.5194/aab-61-87-2018, https://doi.org/10.5194/aab-61-87-2018, 2018
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In this invited review we discuss the value of mice in improving livestock breeding. This review gives an overview of currently available databases for mice that can be used in livestock genetics research. Furthermore, this paper describes how different mouse models have contributed to livestock research in the past.
Allison Fleming, Emhimad A. Abdalla, Christian Maltecca, and Christine F. Baes
Arch. Anim. Breed., 61, 43–57, https://doi.org/10.5194/aab-61-43-2018, https://doi.org/10.5194/aab-61-43-2018, 2018
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Dairy cattle breeders have exploited technological advances in regard to reproduction and genomics. The implementation of such technologies in routine breeding programs has permitted genetic gains in traditional milk production traits as well as, more recently, in low heritability traits like health and fertility. Here we review a number of technologies that have helped shape dairy breeding programs in the past and present, along with those potentially forthcoming.
Sena Ardicli, Hale Samli, Deniz Dincel, Bahadir Soyudal, and Faruk Balci
Arch. Anim. Breed., 60, 303–313, https://doi.org/10.5194/aab-60-303-2017, https://doi.org/10.5194/aab-60-303-2017, 2017
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The impact of polymorphisms of the calpain 1 (CAPN1), calpastatin (CAST), leptin (LEP) and growth hormone receptor (GHR) on carcass characteristics and meat quality traits in 400 purebred Holstein bulls was examined using polymerase chain reaction and restriction fragment length polymorphism method. In the current study, the CAPN1, CAST and GHR genotypes confirmed significant associations with important traits in adequate numbers of animals.
Hamed Amirpour Najafabadi, Saeid Ansari Mahyari, Mohammad Ali Edriss, and Eva Strapakova
Arch. Anim. Breed., 59, 387–393, https://doi.org/10.5194/aab-59-387-2016, https://doi.org/10.5194/aab-59-387-2016, 2016
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This study aimed to use survival analysis and examine the factors affecting functional herd life (FHL) of cows in Isfahan using the Weibull proportional risk model in Isfahan to estimate of breeding values for functional herd life. The SC, milk production, age at first calving and milk period showed significant effects on LPL (P < 0.001) according to the likelihood ratio test. Although there were some fluctuations in genetic trends, an overall increase was observed which leads to a longer FHL
Eva Strapáková, Juraj Candrák, and Peter Strapák
Arch. Anim. Breed., 59, 329–335, https://doi.org/10.5194/aab-59-329-2016, https://doi.org/10.5194/aab-59-329-2016, 2016
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The advantages of increasing lactation persistency in dairy cattle are indisputable on the practical herd level. More persistent lactation brings a longer high-production period. In this study estimate the breeding values of lactation persistency, test day of milk yield, somatic cell score, reproductive traits (calving interval, days open), and longevity in Slovak Holstein dairy cattle were estimated and the relationship between persistency of lactation and other selected trait was analyzed.
Xiaojuan Long, Xibi Fang, Ping Jiang, Hang Xiao, Haibin Yu, Mengjiao Zhou, Yunzhi Pan, Chunyan Lu, Zhihui Zhao, and Runjun Yang
Arch. Anim. Breed., 59, 301–307, https://doi.org/10.5194/aab-59-301-2016, https://doi.org/10.5194/aab-59-301-2016, 2016
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AGPAT6 is a key candidate gene in the lipid metabolism pathway. We detected two single nucleotide polymorphisms (SNPs) in bovine AGPAT6 exons, and we analyzed 33 traits associated with meat quality and the carcass of Chinese Simmental cattle. SNP1 was significantly associated with back fat thickness and fat coverage rate. SNP2 was significantly associated with fat coverage rate and marbling score. Thus, the SNPs of AGPAT6 may be genetic factors influencing carcass composition of beef cattle.
Hafedh Ben Zaabza, Abderrahmen Ben Gara, Hedi Hammami, Mohamed Amine Ferchichi, and Boulbaba Rekik
Arch. Anim. Breed., 59, 243–248, https://doi.org/10.5194/aab-59-243-2016, https://doi.org/10.5194/aab-59-243-2016, 2016
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A Bayesian and REML analyses were used on Tunisian dairy cattle data. Genetic parameters for 305-day milk, fat, and protein yields were estimated. Heritability estimates by using Bayesian method ranged from 0.187 to 0.273, and slightly higher than the corresponding REML. Large genetic correlations (> 0.88) among milk, fat, and protein yields were found for the two methods. This study suggests that results from both methods were reasonably similar to suggest both methods can be used.
Hafedh Ben Zaabza, Abderrahmen Ben Gara, Hedi Hammami, Borni Jemmali, Mohamed Amine Ferchichi, and Boulbaba Rekik
Arch. Anim. Breed., 59, 209–213, https://doi.org/10.5194/aab-59-209-2016, https://doi.org/10.5194/aab-59-209-2016, 2016
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Genetic parameters for 11 456 Tunisian Holstein cows were estimated for the following five reproductive traits: calving interval (CI), calving to first service interval, calving to conception interval (CCI), first service to conception interval and number of services per conception. Low heritabilities were estimated for these traits, and genetic correlation estimates between them were moderately high. The CCI–CI genetic correlation was 0.85, indicating that they are the same trait genetically.
K. Abfalter, W. Brade, and O. Distl
Arch. Anim. Breed., 59, 71–77, https://doi.org/10.5194/aab-59-71-2016, https://doi.org/10.5194/aab-59-71-2016, 2016
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Estimated breeding values (EBVs), relative breeding values (RBVs), and daughter yield deviations of Holstein cows with exceptional longevity (more than nine lactations completed) and the RBVs of their sires were analyzed. Exceptional cows had on average significantly lower EBVs for yield traits but significantly higher RBVs for somatic cell score (RZS) and functional longevity (RZN). Correlations among the proportion of exceptional cows per sire and RZN, RZS as well as fitness were positive.
Cited articles
Alberti, P., Panea, B., Sanudo, C., Olleta, J., Ripoll, G., Ertbjerg, P., Christensen, M., Gigli, S., Failla, S., and Concetti, S.: Live weight, body size and carcass characteristics of young bulls of fifteen European breeds, Livest. Sci., 114, 19–30, 2008.
Allais, S., Journaux, L., Leveziel, H., Payet-Duprat, N., Raynaud, P., Hocquette, J. F., Lepetit, J., Rousset, S., Denoyelle, C., Bernard-Capel, C., and Renand, G.: Effects of polymorphisms in the calpastatin and mu-calpain genes on meat tenderness in 3 French beef breeds, J. Anim. Sci., 89, 1–11, 2011.
Banos, G., Woolliams, J., Woodward, B., Forbes, A., and Coffey, M.: Impact of single nucleotide polymorphisms in leptin, leptin receptor, growth hormone receptor, and diacylglycerol acyltransferase (DGAT1) gene loci on milk production, feed, and body energy traits of UK dairy cows, J. Dairy Sci., 91, 3190–3200, 2008.
Botstein, D., White, R. L., Skolnick, M., and Davis, R. W.: Construction of a genetic linkage map in man using restriction fragment length polymorphisms, Am. J. Hum. Genet., 32, 314–331, 1980.
Buchanan, F. C., Fitzsimmons, C. J., Van Kessel, A. G., Thue, T. D., Winkelman-Sim, D. C., and Schmutz, S. M.: Association of a missense mutation in the bovine leptin gene with carcass fat content and leptin mRNA levels, Genet. Sel. Evol., 34, 105–116, 2002.
Casas, E., Shackelford, S. D., Keele, J. W., Koohmaraie, M., Smith, T. P., and Stone, R. T.: Detection of quantitative trait loci for growth and carcass composition in cattle, J. Anim. Sci., 81, 2976–2983, 2003.
Cerit, H., Dumen, E., and Sezgin, F. H.: Comparision of DGAT1 K232A polymorphism and its effects on some milk quality parameters in Holstein and Native Black Race cattles, Kafkas Univ. Vet. Fak. Derg., 20, 301–305, 2014.
Cheong, H. S., Yoon, D. H., Park, B. L., Kim, L. H., Bae, J. S., Namgoong, S., Lee, H. W., Han, C. S., Kim, J. O., Cheong, I. C., and Shin, H. D.: A single nucleotide polymorphism in CAPN1 associated with marbling score in Korean cattle, BMC Genet., 9, 33–39, 2008.
Chessa, S., Nicolazzi, E. L., Nicoloso, L., Negrini, R., Marino, R., Vicario, D., Marsan, P. A., Valentini, A., and Stefanon, B.: Analysis of candidate SNPs affecting milk and functional traits in the dual-purpose italian Simmental cattle, Livest. Sci., 173, 1–8, 2015.
Clempson, A., Pollott, G., Brickell, J., Bourne, N., Munce, N., and Wathes, D.: Evidence that leptin genotype is associated with fertility, growth, and milk production in Holstein cows, J. Dairy Sci., 94, 3618–3628, 2011.
Corva, P., Soria, L., Schor, A., Villarreal, E., Cenci, M. P., Motter, M., Mezzadra, C., Melucci, L., Miquel, C., and Paván, E.: Association of CAPN1 and CAST gene polymorphisms with meat tenderness in Bos taurus beef cattle from Argentina, Genet. Mol. Biol., 30, 1064–1069, 2007.
Corva, P. M., Fernandez Macedo, G. V., Soria, L. A., Papaleo Mazzucco, J., Motter, M., Villarreal, E. L., Schor, A., Mezzadra, C. A., Melucci, L. M., and Miquel, M. C.: Effect of leptin gene polymorphisms on growth, slaughter and meat quality traits of grazing Brangus steers, Genet. Mol. Res., 8, 105–116, 2009.
Curi, R., Chardulo, L., Mason, M., Arrigoni, M., Silveira, A., and De Oliveira, H.: Effect of single nucleotide polymorphisms of CAPN1 and CAST genes on meat traits in Nellore beef cattle (Bos indicus) and in their crosses with Bos taurus, Anim. Genet., 40, 456–462, 2009.
Da Silva, R., Ferraz, J., Meirelles, F., Eler, J., Balieiro, J., Cucco, D., Mattos, E., Rezende, F., and Silva, S.: Association of single nucleotide polymorphisms in the bovine leptin and leptin receptor genes with growth and ultrasound carcass traits in Nellore cattle, Genet. Mol. Res., 11, 3721–3728, 2012.
Di Stasio, L., Destefanis, G., Brugiapaglia, A., Albera, A., and Rolando, A.: Polymorphism of the GHR gene in cattle and relationships with meat production and quality, Anim. Genet., 36, 138–140, 2005.
Erken, E., Gunesacar, R., and Ozer, H. T.: Investigation of C5a receptor gene 450 C/T polymorphism in Turkish patients with familial Mediterranean fever, Mol. Biol. Rep., 37, 273–276, 2010.
Fortes, M. R., Curi, R. A., Chardulo, L. A., Silveira, A. C., Assumpcao, M. E., Visintin, J. A., and de Oliveira, H. N.: Bovine gene polymorphisms related to fat deposition and meat tenderness, Genet. Mol. Biol., 32, 75–82, 2009.
Friedman, J. M. and Halaas, J. L.: Leptin and the regulation of body weight in mammals, Nature, 395, 763–770, 1998.
Giblin, L., Butler, S. T., Kearney, B. M., Waters, S. M., Callanan, M. J., and Berry, D. P.: Association of bovine leptin polymorphisms with energy output and energy storage traits in progeny tested Holstein-Friesian dairy cattle sires, BMC Genet., 11, 73–82, 2010.
Gill, J. L., Bishop, S. C., McCorquodale, C., Williams, J. L., and Wiener, P.: Association of selected SNP with carcass and taste panel assessed meat quality traits in a commercial population of Aberdeen Angus-sired beef cattle, Genet. Sel. Evol., 41, 36–47, 2009.
Green, M. R. and Sambrook, J.: Isolation of high-molecular-weight DNA from mammalian cells using proteinase K and phenol, in: Molecular Cloning: A Laboratory Manual, edited by: Green, M. R. and Sambrook, J., 4th edition, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, USA, 47–48, 2012.
Hanusova, L., Mikova, A., Vecerek, L., Schroeffelova, D., Rehout, V., Tothova, L., Vernerova, K., Hosnedlova, B., and Citek, J.: Effect of DGAT1 polymorphisms on the estimated breeding values of Czech Simmental sires, Czech J. Anim. Sci., 59, 365–373, 2014.
Hradecka, E., Citek, J., Panicke, L., Rehout, V., and Hanusova, L.: The relation of GH1, GHR and DGAT1 polymorphisms with estimated breeding values for milk production traits of German Holstein sires, Czech J. Anim. Sci., 53, 238–245, 2008.
Journaux, L.: Beef carcass grading and meat quality measurements in different countries and how ICAR is going to use such information, in: Evaluation of carcass and meat quality in cattle and sheep, edited by: Lazzaroni, C., Gigli, S., and Gabina, D., Wageningen Academic Publishers, Wageningen, Netherlands, 50–51, 2007.
Juszczuk-Kubiak, E., Rosochacki, S. J., Wicinska, K., and Szreder, T. S.: A novel RFLP/AluI polymorphism of the bovine calpastatin (CAST) gene and its association with selected traits of beef, Anim. Sci. Pap. Rep., 22, 195–204, 2004.
Koknaroglu, H., Loy, D., Wilson, D., Hoffman, M., and Lawrence, J.: Factors affecting beef cattle performance and profitability, Prof. Anim. Sci., 21, 286–296, 2005.
Koohmaraie, M.: Muscle proteinases and meat aging, Meat Sci., 36, 93–104, 1994.
Kulig, H. and Kmiec, M.: Association between leptin gene polymorphisms and growth traits in Limousin cattle, Russ. J. Genet., 45, 738–741, 2009.
Kulig, H., Kmiec, M., and Wojdak-Maksymiec, K.: Associations between leptin gene polymorphisms and somatic cell count in milk of Jersey cows, Acta Vet. Brno, 79, 237–242, 2010.
Lacorte, G., Machado, M., Martinez, M., Campos, A., Maciel, R., Verneque, R., Teodoro, R., Peixoto, M., Carvalho, M., and Fonseca, C.: DGAT1 K232A polymorphism in Brazilian cattle breeds, Genet. Mol. Res., 5, 475–482, 2006.
Lagonigro, R., Wiener, P., Pilla, F., Woolliams, J., and Williams, J.: A new mutation in the coding region of the bovine leptin gene associated with feed intake, Anim. Genet., 34, 371–374, 2003.
Li, X., Ekerljung, M., Lundstrom, K., and Lunden, A.: Association of polymorphisms at DGAT1, leptin, SCD1, CAPN1 and CAST genes with color, marbling and water holding capacity in meat from beef cattle populations in Sweden, Meat Sci., 94, 153–158, 2013.
Liefers, S. C., te Pas, M. F., Veerkamp, R. F., Chilliard, Y., Delavaud, C., Gerritsen, R., and van der Lende, T.: Association of leptin gene polymorphisms with serum leptin concentration in dairy cows, Mamm. Genome, 14, 657–663, 2003.
Lisa, C. and Di Stasio, L.: Variability of μ-calpain and calpastatin genes in cattle, Ital. J. Anim. Sci., 8, 99–101, 2009.
Lusk, J. L.: Association of single nucleotide polymorphisms in the leptin gene with body weight and backfat growth curve parameters for beef cattle, J. Anim. Sci., 85, 1865–1872, 2007.
Maharani, D., Jung, Y., Jung, W., Jo, C., Ryoo, S., Lee, S., Yeon, S., and Lee, J.: Association of five candidate genes with fatty acid composition in Korean cattle, Mol. Biol. Rep., 39, 6113–6121, 2012.
Melucci, L. M., Panarace, M., Feula, P., Villarreal, E. L., Grigioni, G., Carduza, F., Soria, L., Mezzadra, C. A., Arceo, M., Mazzucco, J. P., Corva, P. M., Irurueta, M., Rogberg-Munoz, A., and Miquel, M. C.: Genetic and management factors affecting beef quality in grazing Hereford steers, Meat. Sci., 92, 768–774, 2012.
Miquel, M. C., Villarreal, E., Mezzadra, C., Melucci, L., Soria, L., Corva, P., and Schor, A.: The association of CAPN1 316 marker genotypes with growth and meat quality traits of steers finished on pasture, Genet. Mol. Biol., 32, 491–496, 2009.
Mundan, D., Gogebakan, S., Ergun, C., and Kaban, I. H.: Evaluation of fattening performance of Holstein cattle at different initial weights under summer season conditions in the district of Silifke of Mersin province, J. Anim. Vet. Adv., 11, 186–190, 2012.
Nkrumah, J. D., Li, C., Yu, J., Hansen, C., Keisler, D. H., and Moore, S. S.: Polymorphisms in the bovine leptin promoter associated with serum leptin concentration, growth, feed intake, feeding behavior, and measures of carcass merit, J. Anim. Sci., 83, 20–28, 2005.
Nkrumah, J. D., Li, C., Keisler, D. H., Sherman, E. L., Wang, Z., Murdoch, B. M., and Moore, S. S.: Polymorphisms in the leptin gene and their associations with performance, feed efficiency, and carcass merit of beef cattle, 8th World Congress on Genetics Applied to Livestock Production, Belo Horizonte, MG, Brasil, 13–18 August 2006.
Nkrumah, J. D., Keisler, D. H., Crews, D. H., Basarab, J. A., Wang, Z., Li, C., Price, M. A., Okine, E. K., and Moore, S. S.: Genetic and phenotypic relationships of serum leptin concentration with performance, efficiency of gain, and carcass merit of feedlot cattle, J. Anim. Sci., 85, 47–55, 2007.
Ozluturk, A., Tuzemen, N., Yener, M., Esenbuga, N., and Dursun, E.: Fattening performance, carcass traits and meat quality characteristics of calves sired by Charolais, Simmental and Eastern Anatolian Red sires mated to Eastern Anatolian Red dams, Meat Sci., 67, 463–470, 2004.
Oztabak, K., Toker, N. Y., Un, C., and Akis, I.: Leptin gene polymorphisms in native Turkish cattle breeds, Kafkas Univ. Vet. Fak. Derg., 16, 921–924, 2010.
Page, B. T., Casas, E., Quaas, R. L., Thallman, R. M., Wheeler, T. L., Shackelford, S. D., Koohmaraie, M., White, S. N., Bennett, G. L., Keele, J. W., Dikeman, M. E., and Smith, T. P.: Association of markers in the bovine CAPN1 gene with meat tenderness in large crossbred populations that sample influential industry sires, J. Anim. Sci., 82, 3474–3481, 2004.
Pfuhl, R., Bellmann, O., Kühn, C., Teuscher, F., Ender, K., and Wegner, J.: Beef versus dairy cattle: a comparison of feed conversion, carcass composition, and meat quality, Arch. Tierz., 50, 59–70, 2007.
Pinto, L. F., Ferraz, J. B., Meirelles, F. V., Eler, J. P., Rezende, F. M., Carvalho, M. E., Almeida, H. B., and Silva, R. C.: Association of SNPs on CAPN1 and CAST genes with tenderness in Nellore cattle, Genet. Mol. Res., 9, 1431–1442, 2010.
Pintos, D. and Corva, P. M.: Association between molecular markers for beef tenderness and growth traits in Argentinian angus cattle, Anim. Genet., 42, 329–332, 2011.
Reardon, W., Mullen, A., Sweeney, T., and Hamill, R.: Association of polymorphisms in candidate genes with colour, water-holding capacity, and composition traits in bovine M. longissimus and M. semimembranosus, Meat Sci., 86, 270–275, 2010.
Schenkel, F., Miller, S., Jiang, Z., Mandell, I., Ye, X., Li, H., and Wilton, J.: Association of a single nucleotide polymorphism in the calpastatin gene with carcass and meat quality traits of beef cattle, J. Anim. Sci., 84, 291–299, 2006.
Sherman, E., Nkrumah, J., Murdoch, B., Li, C., Wang, Z., Fu, A., and Moore, S.: Polymorphisms and haplotypes in the bovine neuropeptide Y, growth hormone receptor, ghrelin, insulin-like growth factor 2, and uncoupling proteins 2 and 3 genes and their associations with measures of growth, performance, feed efficiency, and carcass merit in beef cattle, J. Anim. Sci., 86, 1–16, 2008.
Shin, S. and Chung, E. R.: Association of SNP marker in the leptin gene with carcass and meat quality traits in Korean cattle, Asian-Aust. J. Anim. Sci., 20, 1–6, 2007.
Shin, S. C., Heo, J. P., and Chung, E. R.: Genetic variants of the FABP4 gene are associated with marbling scores and meat quality grades in Hanwoo (Korean cattle), Mol. Biol. Rep., 39, 23–30, 2012.
Silva, D., Crispim, B., Silva, L., Oliveira, J., Siqueira, F., Seno, L., and Grisolia, A.: Genetic variations in the leptin gene associated with growth and carcass traits in Nellore cattle, Genet. Mol. Res., 13, 3002–3012, 2014.
Soria, L. A., Corva, P., Huguet, M., Mino, S., and Miquel, M.: Bovine μ-calpain (CAPN1) gene polymorphisms in Brangus and Brahman bulls, J. Basic Appl. Sci., 21, 61–69, 2010.
Stone, R. T., Kappes, S. M., and Beattie, C. W.: The bovine homolog of the obese gene maps to chromosome 4, Mamm. Genome, 7, 399–400, 1996.
Tait, R. G., Shackelford, S. D., Wheeler, T. L., King, D. A., Keele, J. W., Casas, E., Smith, T. P., and Bennett, G. L.: CAPN1, CAST, and DGAT1 genetic effects on preweaning performance, carcass quality traits, and residual variance of tenderness in a beef cattle population selected for haplotype and allele equalization, J. Anim. Sci., 92, 5382–5393, 2014.
Waters, S., McCabe, M., Howard, D., Giblin, L., Magee, D., MacHugh, D., and Berry, D.: Associations between newly discovered polymorphisms in the Bos taurus growth hormone receptor gene and performance traits in Holstein–Friesian dairy cattle, Anim. Genet., 42, 39–49, 2011.
Yazdani, H., Rahmani, H., Edris, M., and Dirandeh, E.: Association between A59V polymorphism in exon 3 of leptin gene and reproduction traits in cows of Iranian Holstein, Afr. J. Biotechnol., 9, 5997–6000, 2010.
Yousefi, S. and Azari, M. A.: Study of Calpastatin Gene Polymorphism in Holstein Cattle and Buffalo, Anim. Sci. Biotech., 45, 285–288, 2012.
Short summary
The present study was based on the association of polymorphisms at LEP, CAST, CAPN1, GHR, FABP4 and DGAT1 genes with fattening performance and carcass traits in Simmental bulls. Results indicated that final weight, fattening period, total weight gain and average daily gain differentiated the CAST and CAPN1 marker genotypes. Moreover, a novel effect of the LEP A80V on carcass weight and dressing percentage was observed. The results could be indicative for future studies on beef production.
The present study was based on the association of polymorphisms at LEP, CAST, CAPN1, GHR, FABP4...