Articles | Volume 60, issue 2
https://doi.org/10.5194/aab-60-51-2017
https://doi.org/10.5194/aab-60-51-2017
Original study
 | 
05 Apr 2017
Original study |  | 05 Apr 2017

Genome-wide QTL mapping results for regional DXA body composition and bone mineral density traits in pigs

Sophie Rothammer, Maren Bernau, Prisca V. Kremer-Rücker, Ivica Medugorac, and Armin M. Scholz

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Cited articles

Alam, I., Carr, L. G., Liang, T., Liu, Y., Edenberg, H. J., Econs, M. J., and Turner, C. H.: Identification of genes influencing skeletal phenotypes in congenic P/NP rats, J. Bone Miner. Res., 25, 1314–1325, https://doi.org/10.1002/jbmr.8, 2010.
Ames, S. K., Ellis, K. J., Gunn, S. K., Copeland, K. C., and Abrams, S. A.: Vitamin D receptor gene Fok1 polymorphism predicts calcium absorption and bone mineral density in children, J. Bone Miner. Res., 14, 740–746, https://doi.org/10.1359/jbmr.1999.14.5.740, 1999.
Arlot, M. E., Sornay-Rendu, E., Garnero, P., Vey-Marty, B., and Delmas, P. D.: Apparent pre- and postmenopausal bone loss evaluated by DXA at different skeletal sites in women: the OFELY cohort, J. Bone Miner. Res., 12, 683–690, https://doi.org/10.1359/jbmr.1997.12.4.683, 1997.
Beamer, W. G., Shultz, K. L., Donahue, L. R., Churchill, G. A., Sen, S., Wergedal, J. R., Baylink, D. J., and Rosen, C. J.: Quantitative trait loci for femoral and lumbar vertebral bone mineral density in C57BL/6J and C3H/HeJ inbred strains of mice, J. Bone Miner. Res., 16, 1195–1206, https://doi.org/10.1359/jbmr.2001.16.7.1195, 2001.
Bian, Y. and Holland, J. B.: Ensemble Learning of QTL Models Improves Prediction of Complex Traits, G3 (Bethesda), 5, 2073–2084, https://doi.org/10.1534/g3.115.021121, 2015.
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Short summary
In a previous mapping study including body composition and bone mineral traits obtained by DXA scans, QTL for bone mineral traits were rare. This study aimed to clarify if the mapping results were influenced by the analysed body regions. Hence, analyses were repeated using the same material (551 pigs) and methods but two manually defined body regions instead of the initial whole-body setting. Our results show an overall high consistency of mapping results especially for body composition traits.