Articles | Volume 59, issue 3
https://doi.org/10.5194/aab-59-351-2016
https://doi.org/10.5194/aab-59-351-2016
Original study
 | 
11 Aug 2016
Original study |  | 11 Aug 2016

Exploration of the exonic variations of the iPSC-related Nanog gene and their effects on phenotypic traits in cattle

Meng Zhang, Chuanying Pan, Qin Lin, Shenrong Hu, Ruihua Dang, Chuzhao Lei, Hong Chen, and Xianyong Lan

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Latest update: 21 Nov 2024
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Short summary
Nanog is an important pluripotent transcription regulator, and its overexpression leads to a high expression of the growth and differentiation factor 3, affecting animal growth traits. The aim of this study was to explore the genetic variations within the Nanog gene and their effects on phenotypic traits in cattle. Six novel exonic single nucleotide polymorphisms were found in six cattle breeds and indicated that Nanog could be a candidate gene for marker-assisted selection in cattle breeding.