Articles | Volume 69, issue 4
https://doi.org/10.5194/aab-69-553-2026
https://doi.org/10.5194/aab-69-553-2026
Original study
 | 
06 Oct 2026
Original study |  | 06 Oct 2026

Unveiling potential genetic markers: associations of IGF1R eon 13 and Intronic polymorphisms with growth traits in yak

Xinyue Liu, Yincang Han, Yonggang Sun, Fajie Gou, Jianyu Chen, Weiqiang Jiang, and Qingye Zhao

Cited articles

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Annunziata, M., Granata, R., and Ghigo, E.: The IGF system, Acta Diabetol., 48, 1–9, https://doi.org/10.1007/s00592-010-0227-z, 2011. a
Cartegni, L., Chew, S., and Krainer, A.: Listening to silence and understanding nonsense: exonic mutations that affect splicing, Nat. Rev. Genet., 3, 285–298, https://doi.org/10.1038/nrg775, 2002. a
Chiang, H., Chen, Y., Su, J., Lin, H., Yu, C., Hung, Y., Wang, Y., Huang, Y., and Lin, C.: Mechanism and modeling of human disease-associated near-exon intronic variants that perturb RNA splicing, Nat. Struct. Mol. Biol., 29, 1043–1055, https://doi.org/10.1038/s41594-022-00844-1, 2022. a, b
DeChiara, T. M., Efstratiadis, A., and Robertson, E. J.: A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting, Nature, 345, 78–80, https://doi.org/10.1038/345078a0, 1990. a
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Short summary
We studied 400 female yaks from the Qinghai Plateau to explore whether small differences in a growth-related gene were linked to body size. Several genetic differences were associated with height and body length, and one genetic pattern was linked to better overall growth. These findings may help identify yaks with favorable growth potential and support more efficient breeding in the future.
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