Articles | Volume 69, issue 2
https://doi.org/10.5194/aab-69-265-2026
https://doi.org/10.5194/aab-69-265-2026
Original study
 | 
30 Apr 2026
Original study |  | 30 Apr 2026

Protective effect of dietary L-carnitine supplementation on follicular development in the ovary of ewes with subclinical pregnancy toxemia

Ali Osman Turgut, Merve Pekince Özöner, Davut Koca, Ebru Karakaya Bilen, Fatma İşbilir, Özgür Özöner, Ali Ünver, Mehmet Eroğlu, Çiğdem Bolaç, Muhammed Hasan Şirin, and İhsan İşbilir

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Cited articles

Abreu-Palermo, M. C., Rodríguez-Gamarra, P., Perini-Perera, S., Acosta-Dibarrat, J., Benech-Gulla, A., González-Montaña, J. R., and Cal-Pereyra, L.: Effects of metabolic changes produced in ewes with subclinical pregnancy toxemia over reproductive parameters, Rev. Bras. Zootecn., 50, e20200213, https://doi.org/10.37496/rbz5020200213, 2021. 
Akter, M. M., Tazi, T. J., Alam, M. H., Akter, I., and Moniruzzaman, M.: L-Carnitine modulates oocyte development and cumulus expansion in tropical ruminants: Experimental and bioinformatics insights, Anim. Sci. J., 96, e70102, https://doi.org/10.1111/asj.70102, 2025. 
Bartlewski, P. M., Baby, T. E., and Giffin, J. L.: Reproductive cycles in sheep, Anim. Reprod. Sci., 124, 259–268, https://doi.org/10.1016/j.anireprosci.2011.02.024, 2011. 
Beam, S. W. and Butler, W. R.: Energy balance, metabolic hormones, and early postpartum follicular development in dairy cows fed prilled lipid, J. Dairy Sci., 81, 121–131, https://doi.org/10.3168/jds.S0022-0302(98)75559-6, 1998. 
Bhakty, Z. W., Kaiin, N. W. K., Karja, N. W. K., and Setiadi, I. M. W.: L-Carnitine supplementation enhances nuclear and cytoplasmic maturation rates of sheep oocytes in vitro, Trop. Anim. Sci. J., 44, 131–137, https://doi.org/10.5398/tasj.2021.44.2.131, 2021. 
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Short summary
This study examined the effects of subclinical pregnancy toxemia (SPT) on follicular development and evaluated the protective potential of L-carnitine supplementation in ewes. İn this study, our results highlight the importance of adequate nutrition and metabolic support during late gestation, suggesting that L-carnitine supplementation may enhance follicular growth and reproductive performance in ewes with SPT.
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