A novel 12 bp deletion within goat LHX4 gene significantly affected litter size
Hailong Yan,Fei Zhang,Ke Wang,Jinwang Liu,Haijing Zhu,Chuanying Pan,and Lei Qu
Hailong Yan
Shaanxi Provincial Engineering and Technology Research Center of
Cashmere Goats, Yulin University, Yulin 719000, China
Life Science Research Center, Yulin University, Yulin 719000, China
College of Animal Science and Technology, Northwest A&F University,
Shaanxi Key Laboratory of Molecular Biology for Agriculture, Yangling,
712100 Shaanxi, China
Fei Zhang
Innovation Experimental College, Northwest A&F University, Yangling
712100, China
Ke Wang
College of Animal Science and Technology, Northwest A&F University,
Shaanxi Key Laboratory of Molecular Biology for Agriculture, Yangling,
712100 Shaanxi, China
Jinwang Liu
Shaanxi Provincial Engineering and Technology Research Center of
Cashmere Goats, Yulin University, Yulin 719000, China
Life Science Research Center, Yulin University, Yulin 719000, China
Haijing Zhu
Shaanxi Provincial Engineering and Technology Research Center of
Cashmere Goats, Yulin University, Yulin 719000, China
Life Science Research Center, Yulin University, Yulin 719000, China
Chuanying Pan
College of Animal Science and Technology, Northwest A&F University,
Shaanxi Key Laboratory of Molecular Biology for Agriculture, Yangling,
712100 Shaanxi, China
In this study, a novel 12 bp indel within the LHX4 gene first intron was firstly found. Meanwhile, the association analysis indicated that the 12 bp indel was significantly associated with litter size in 1149 Shaanbei cashmere goats (P < 0.05). The litter sizes of genotype DD and ID individuals were superior to those of genotype II, implying that the 12 bp indel might affect litter size. These results could provide a new insight into implementing marker-assisted selection in goat breeding.
In this study, a novel 12 bp indel within the LHX4 gene first intron was firstly found....
