Articles | Volume 59, issue 1
https://doi.org/10.5194/aab-59-151-2016
© Author(s) 2016. This work is distributed under
the Creative Commons Attribution 3.0 License.
the Creative Commons Attribution 3.0 License.
https://doi.org/10.5194/aab-59-151-2016
© Author(s) 2016. This work is distributed under
the Creative Commons Attribution 3.0 License.
the Creative Commons Attribution 3.0 License.
A novel 17 bp indel in the SMAD3 gene alters transcription level, contributing to phenotypic traits in Chinese cattle
Tao Shi
College of Animal Science and Technology, Northwest A&F
University, Shaanxi Key Laboratory of Molecular Biology for Agriculture,
Yangling, 712100 Shaanxi, China
Wenwen Peng
College of Animal Science and Technology, Northwest A&F
University, Shaanxi Key Laboratory of Molecular Biology for Agriculture,
Yangling, 712100 Shaanxi, China
Jianyu Yan
College of Animal Science and Technology, Northwest A&F
University, Shaanxi Key Laboratory of Molecular Biology for Agriculture,
Yangling, 712100 Shaanxi, China
Hanfang Cai
College of Animal Science and Technology, Northwest A&F
University, Shaanxi Key Laboratory of Molecular Biology for Agriculture,
Yangling, 712100 Shaanxi, China
Xianyong Lan
College of Animal Science and Technology, Northwest A&F
University, Shaanxi Key Laboratory of Molecular Biology for Agriculture,
Yangling, 712100 Shaanxi, China
Chuzhao Lei
College of Animal Science and Technology, Northwest A&F
University, Shaanxi Key Laboratory of Molecular Biology for Agriculture,
Yangling, 712100 Shaanxi, China
Yueyu Bai
Animal Health Supervision in Henan Province, Zhengzhou, 450008 Henan,
China
Hong Chen
CORRESPONDING AUTHOR
College of Animal Science and Technology, Northwest A&F
University, Shaanxi Key Laboratory of Molecular Biology for Agriculture,
Yangling, 712100 Shaanxi, China
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Cited
21 citations as recorded by crossref.
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Latest update: 23 Nov 2024
Short summary
SMAD3 plays essential roles in myogenesis and osteogenesis and may relate to the regulation of body weight. In this study, a 17 bp indel in intron3 of the SMAD3 gene was detected in four Chinese cattle breeds (Qinchuan, Jiaxian, Nanyang and Caoyuan) by using DNA pool sequencing, and it was significantly associated with gene expression and growth traits of Qinchuan and Caoyuan cattle. This indel could be could be a promising marker for beef cattle breeding.
SMAD3 plays essential roles in myogenesis and osteogenesis and may relate to the regulation of...