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Volume 51, issue 3
Arch. Anim. Breed., 51, 300–301, 2008
https://doi.org/10.5194/aab-51-300-2008
© Author(s) 2008. This work is distributed under
the Creative Commons Attribution 3.0 License.
Arch. Anim. Breed., 51, 300–301, 2008
https://doi.org/10.5194/aab-51-300-2008
© Author(s) 2008. This work is distributed under
the Creative Commons Attribution 3.0 License.

  10 Oct 2008

10 Oct 2008

Association of polymorphisms of the GHRHR gene with growth traits in cattle (Brief report)

C. Zhang1, H. Chen1,2, L. Zhang1, M. Zhao1, Y. Guo1, C. Zhang1, X. Lan1, and S. Hu1 C. Zhang et al.
  • 1College of Animal Science and Technology, Northwest A&F University, Shaanxi Key Laboratory of Molecular Biology for Agriculture, Yangling, Shaanxi 712100, China
  • 2Institute of Cellular and Molecular Biology, Xuzhou Normal University, Xuzhou, Jiangsu 221116, China

Abstract. The hypothalamic hormone, growth hormone-releasing hormone (GHRH), is the principal stimulator of pituitary growth hormone (GH) synthesis and secretion. Its pituitary receptor is well characterized as a member of the superfamily of G protein-coupled receptors (MAYO et al., 1992). GHRH and its receptor provide important functions in the regulation of the GH axis and in the development and proliferation of pituitary somatotropes (LIN-SU et al., 2002). By now, polymorphisms of bovine GHRHR were not reported. In the present experiment the 5' flanking region, the coding region and partially introns of GHRHR were screened to detect the SNPs in the predominant cattle breeds of China.

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