AAB Archives Animal Breeding AAB Arch. Anim. Breed. 2363-9822 FBN Dummerstorf Göttingen, Germany 10.5194/aab-51-300-2008 Association of polymorphisms of the <i>GHRHR</i> gene with growth traits in cattle (Brief report) Zhang C. 1 Chen H. 1 2 Zhang L. 1 Zhao M. 1 Guo Y. 1 Zhang C. 1 Lan X. 1 Hu S. 1 College of Animal Science and Technology, Northwest A&F University, Shaanxi Key Laboratory of Molecular Biology for Agriculture, Yangling, Shaanxi 712100, China Institute of Cellular and Molecular Biology, Xuzhou Normal University, Xuzhou, Jiangsu 221116, China 10 10 2008 51 3 300 301 Copyright: © 2008 C. Zhang et al. 2008 This work is licensed under the Creative Commons Attribution 3.0 Unported License. To view a copy of this licence, visit https://creativecommons.org/licenses/by/3.0/ This article is available from https://aab.copernicus.org/articles/51/300/2008/aab-51-300-2008.html The full text article is available as a PDF file from https://aab.copernicus.org/articles/51/300/2008/aab-51-300-2008.pdf

The hypothalamic hormone, growth hormone-releasing hormone (GHRH), is the principal stimulator of pituitary growth hormone (GH) synthesis and secretion. Its pituitary receptor is well characterized as a member of the superfamily of G protein-coupled receptors (MAYO et al., 1992). GHRH and its receptor provide important functions in the regulation of the GH axis and in the development and proliferation of pituitary somatotropes (LIN-SU et al., 2002). By now, polymorphisms of bovine <i>GHRHR</i> were not reported. In the present experiment the 5' flanking region, the coding region and partially introns of <i>GHRHR</i> were screened to detect the SNPs in the predominant cattle breeds of China.