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Volume 50, issue 5
Arch. Anim. Breed., 50, 531–532, 2007
https://doi.org/10.5194/aab-50-531-2007
© Author(s) 2007. This work is distributed under
the Creative Commons Attribution 3.0 License.
Arch. Anim. Breed., 50, 531–532, 2007
https://doi.org/10.5194/aab-50-531-2007
© Author(s) 2007. This work is distributed under
the Creative Commons Attribution 3.0 License.

  10 Oct 2007

10 Oct 2007

A new ACRS-SNP in the 5’ flanking region of the bovine insulin-like growth factor 1 (IGF1) gene (Brief report)

S. Zych1, M. Szewczuk2, S. Czerniawska-Piątkowska2, and I. Szatkowska1 S. Zych et al.
  • 1Laboratory of Molecular Cytogenetics, Department of Ruminant Science, Agricultural University of Szczecin, Judyma 10, 71-460 Szczecin, Poland
  • 2Laboratory of Ruminant Improvement, Department of Ruminant Science, Agricultural University of Szczecin, Judyma 10, 71-460 Szczecin, Poland

Abstract. A number of polymorphisms within the bovine insulin-like growth factor 1 (IGF1) gene were described at this time. One of these mutations, a low polymorphic (CA)n microsatellite in the 5’ flanking region of the gene, has been reported by KIRKPATRICK (1992). A T>C transition was identified in the P1 promoter region of the bovine IGF1K gene (GenBank Acc. No. AF017143; GE et al., 2001). LIEN et al. (2000) identified a 4-bp deletion (TTTG) and nine point mutations within non-coding regions of the gene (GenBank Acc. No. AF210383-387). In our study, the sequencing of (CA)n microsatellite fragment revealed another single nucleotide polymorphism (SNP) in the 5’ flanking region of the bovine IGF1 gene. The DNA sequence has been deposited to GenBank under accession number DQ975234.

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