A new ACRS-SNP in the 5’ flanking region of the bovine insulin-like growth factor 1 (IGF1) gene (Brief report)

Abstract. A number of polymorphisms within the bovine insulin-like growth factor 1 (IGF1) gene were described at this time. One of these mutations, a low polymorphic (CA)_n microsatellite in the 5’ flanking region of the gene, has been reported by KIRKPATRICK (1992). A T>C transition was identified in the P1 promoter region of the bovine IGF1K gene (GenBank Acc. No. AF017143; GE et al., 2001). LIEN et al. (2000) identified a 4-bp deletion (TTTG) and nine point mutations within non-coding regions of the gene (GenBank Acc. No. AF210383-387). In our study, the sequencing of (CA)_n microsatellite fragment revealed another single nucleotide polymorphism (SNP) in the 5’ flanking region of the bovine IGF1 gene. The DNA sequence has been deposited to GenBank under accession number DQ975234.