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Volume 49, issue 6
Arch. Anim. Breed., 49, 617–618, 2006
https://doi.org/10.5194/aab-49-617-2006
© Author(s) 2006. This work is distributed under
the Creative Commons Attribution 3.0 License.
Arch. Anim. Breed., 49, 617–618, 2006
https://doi.org/10.5194/aab-49-617-2006
© Author(s) 2006. This work is distributed under
the Creative Commons Attribution 3.0 License.

  10 Oct 2006

10 Oct 2006

Mapping of ACE Gene to Pig Chromosome 12 (Brief Report)

V. Q. Nguyen*, K. L. Glenn, B. E. Mote, and M. F. Rothschild V. Q. Nguyen et al.
  • Department of Animal Science and the Center for Integrated Animal Genomics, Iowa State University, Ames, IA 50011, USA
  • *present address: Department of Biological Science, University of California, Irvine , Irvine, CA 92697, USA

Abstract. In humans, the Angiotensin I Converting Enzyme (ACE) gene is located on the q arm of chromosome 17. It contains 16 exons and 15 introns. The deletion (D) allele of the insertion/deletion polymorphism of the ACE gene has been shown to be associated with a higher risk of coronary artery disease (TANIQUCHI et al., 2001) and hypertension (MORSHED et al., 2002), whereas the insertion (I) allele has been found to be associated with a higher risk of Alzheimer’s disease (ELKINS et al., 2004). Furthermore, a study (LUFT, 1999) associated ACE with longevity. Our hypothesis is that these same genes or regulatory pathways are also important for sow productive life. The objective of this study was to determine the chromosomal location of ACE in the pig by linkage and RH mapping.

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