AAB Archives Animal Breeding AAB Arch. Anim. Breed. 2363-9822 FBN Dummerstorf Göttingen, Germany 10.5194/aab-52-108-2009 <i>Tropomodulin 1 (TMOD1)</i> is associated with lean meat growth and meat quality in the pig (Brief Report) Wu H. 1 Zhao S. 1 Liu B. 1 Yu M. 1 Zhu M. 1 Li C. 1 Fan B. 1 Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction, Ministry of Education & Key Laboratory of Swine Genetics and Breeding of Ministry of Agriculture, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, People’s Republic of China 10 10 2009 52 1 108 110 Copyright: © 2009 H. Wu et al. 2009 This work is licensed under the Creative Commons Attribution 3.0 Unported License. To view a copy of this licence, visit https://creativecommons.org/licenses/by/3.0/ This article is available from https://aab.copernicus.org/articles/52/108/2009/aab-52-108-2009.html The full text article is available as a PDF file from https://aab.copernicus.org/articles/52/108/2009/aab-52-108-2009.pdf

<i>Tropomodulin 1 (TMOD1)</i> is a member of the tropomodulin family, which are highly conserved capping proteins of the pointed ends of the erythrocyte membrane and sarcomeric actin filaments. Tropomodulins are involved in the architecture of the sarcomere in muscle cells and the membrane skeleton in nonmuscle cells (COLUCCIO et al. 1994, GREGORIO et al. 1995). <i>TMOD1</i> is predominantly expressed in vertebrate cardiac muscle and slow twitch muscle fibers, and it binds to one end of tropomyosin (TM) that plays important roles in regulating the function of actin filament (FISCHER et al. 2003, GUNNING et al. 2008). Here we identified a single nucleotide polymorphism (SNP) in the porcine <i>TMOD1</i> gene and further analyzed the effects of this gene on the lean meat growth, meat quality and other related traits in pigs.